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Background and purpose
The aim of the study was to evaluate the metabolic correlates of Apolipoprotein E (APOE) genotype in amyotrophic lateral sclerosis (ALS) and to investigate the role of ε2 as a risk factor for cognitive impairment.
Methods
A total of 159 ALS cases underwent APOE and ALS‐related genes analysis, neuropsychological assessment and cerebral 18F‐2‐fluoro‐2‐deoxy‐D‐glucose positron...
Electronic supplementary material The online version of this article (doi: 10.1007/s00415-016-8327-5 ) contains supplementary material, which is available to authorized users.
Peritoneal carcinomatosis is a common evolution of neoplasms and the terminal stage of disease. A new therapeutic technique, based on the total surgical removal of peritoneal lesions (peritonectomy procedure – PP) combined with the intraperitoneal chemohyperthermia (IPCH), has been developed. Proper patient selection is mandatory for optimizing the results of treatment. The aim of this study was to...
A young patient with undefined autoimmune lymphoproliferative syndrome (ALPS-U) and low back pain underwent a CT and MRI study that showed enhancing vertebral lesions, some pulmonary nodules and diffuse latero-cervical lymphadenopathy. A 18 F-FDG-PET/CT scan showed many areas of intense 18 F-FDG uptake in multiple vertebrae, in some ribs, in the sacrum, in the liver, in both lungs,...
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