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An overabundant discharge of inflammatory mediators plays a significant role in intestinal injury throughout the early stages of critical burns. The present study aims to explore the outcome of 200mM hypertonic saline (HS) resuscitation on the intestinal injury of critically burned rats.Fifty-six Sprague-Dawley rats were randomized into three groups: sham group (group A), burn plus lactated Ringer’s...
Excessive release of inflammatory mediators and oxidative stress play important roles in the increased vascular permeability and systemic edema during the early stage of severe burn. This study investigates the effect of 200 mEq/L Na + hypertonic saline (HS) on systemic inflammatory response and oxidative stress in severely burned rats.Sprague-Dawley rats were divided into three groups: sham...
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