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An overabundant discharge of inflammatory mediators plays a significant role in intestinal injury throughout the early stages of critical burns. The present study aims to explore the outcome of 200mM hypertonic saline (HS) resuscitation on the intestinal injury of critically burned rats.Fifty-six Sprague-Dawley rats were randomized into three groups: sham group (group A), burn plus lactated Ringer’s...
Puerarin, the main isoflavone glycoside extracted from the root of Pueraria lobata, is widely prescribed for patients with cardiovascular disorders in China. This study investigates the effect of puerarin on severe burn-induced acute myocardial injury in rats and its underlying mechanisms.Healthy adult Wistar rats were divided into three groups: (1) sham group, sham burn treatment; (2) burn group,...
Excessive release of inflammatory mediators and oxidative stress play important roles in the increased vascular permeability and systemic edema during the early stage of severe burn. This study investigates the effect of 200 mEq/L Na + hypertonic saline (HS) on systemic inflammatory response and oxidative stress in severely burned rats.Sprague-Dawley rats were divided into three groups: sham...
The Chinese peasants in the middle of Anhui Province and north of Dabieshan Mountain are accustomed to using industrial alcohol to kindle honeycomb briquettes in their household coal stoves. Pouring alcohol into the stove often results in flame burns when the honeycomb briquettes inside are not completely extinguished. The purpose of this study is to describe the unique cause and clinical characteristics...
The aim of this retrospective, comparative study was to analyse the management of extensive burns so as to decrease morbidity and mortality. Over 1987–1996, 24 people with burns >80% of total body surface area and >50% full-thickness burn were admitted to the burn unit of Anhui Medical University Hospital (group A); 30 similar admissions over 1997–2006 formed group B. No significant difference...
The aim of this study was to evaluate the epidemiology of burns due to gunpowder explosions in fireworks factories. Three hundred and fifty-one patients having burns caused by gunpowder explosions in a fireworks factory were admitted to our center from 1 January 1987 to 31 December 1999 and the clinical notes of 339 patients were available for review. Data on age, sex, size, depth and sites of burn,...
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