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In a previous paper (VanAerts et al., Toxicology in Vitro 1993, 7, 769-775) we have shown that the embryotoxicity of cyclophosphamide was greatly enhanced when cyclophosphamide had been added to a primary hepatocyte culture derived from Aroclor 1254-pretreated male rats (M A ) and the medium from this culture was added to a post-implantation rat embryo culture. However, when medium from hepatocytes...