Search results for: Jun‐Mei Zhang

Items from 1 to 20 out of 27 results

article

Paraneoplastic pemphigus misdiagnosed as juvenile dermatomyositis: A case report

Feng‐Qiao Gao, Jun‐Mei Zhang, Cai‐Feng Li

International Journal of Rheumatic Diseases > 26 > 9 > 1826 - 1829

Paraneoplastic pemphigus (PNP) is a rare autoimmune skin disease closely related to tumors, characterized by a maculopapular rash with mucosal pain, bronchiole occlusion, and respiratory failure may occur over time, even resulting in death. We report a rare case of a child with autoimmune PNP misdiagnosed as juvenile dermatomyositis (JDM), and summarize the key points of differentiation of clinical...

article

Comparison of different sedatives in children before general anaesthesia for selective surgery: A network meta‐analysis

Chuan‐Qi Yang, Kai‐Hua Yu, Rong‐Rong Huang, Shan‐Shan Qu, more

Journal of Clinical Pharmacy and Therapeutics > 47 > 10 > 1495 - 1505

What is known and Objective It is estimated that 60% of children undergoing anaesthesia develop severe preoperative anxiety. The anxiety is associated with adverse reactions. Sedatives such as dexmedetomidine, midazolam, clonidine, ketamine, and melatonin can be used as premedication against preoperative anxiety. However, no consensus has been reached on the choice of pre‐anaesthetic sedatives in...

article

Analysis of three-dimensional endocardial and epicardial strains from cardiac magnetic resonance in healthy subjects and patients with hypertrophic cardiomyopathy

Xiaodan Zhao, Ru San Tan, Hak Chiaw Tang, Shuang Leng, more

Medical & Biological Engineering & Computing > 2018 > 56 > 1 > 159-172

Hypertrophic cardiomyopathy (HCM) is a genetic disease that leads to left ventricle (LV) hypertrophy with or without the presence of LV outflow tract obstruction. The aim of this study was to find an easy and useful indicator based on cardiac magnetic resonance (CMR) images for control subjects and patients with and without obstruction. CMR scans were performed for 19 control subjects and 19 HCM patients...

article

Cardiac MRI based numerical modeling of left ventricular fluid dynamics with mitral valve incorporated

Boyang Su, Ru San Tan, Ju Le Tan, Kenneth Wei Qiang Guo, more

Journal of Biomechanics > 2016 > 49 > 7 > 1199-1205

Recent numerical studies were focused on the modeling of flow in patient-specific left ventricle (LV); however, the mitral valve (MV) was usually excluded. In this study, both patient-specific LV and MV were modeled to achieve a more realistic intraventricular flow. Cardiac MRI images were acquired from a pulmonary arterial hypertension (PAH) patient and a healthy volunteer, and manual segmentation...

chapter

Group-Oriented (t, n) Threshold Digital Signature Schemes with Traceable Signers

Zi-Chen Li, Yi-Qi Dai, Jun-Mei Zhang, Jun Luo, more

Lecture Notes in Computer Science > Electronic Commerce Technologies > Trust and Security > 57-69

In this paper, we propose two group-oriented ) , ( n t threshold digital signature schemes with traceable signers. One needs the assistance of a mutually trusted center, the other does not need the assistance of a mutually trusted center. We also discuss the security and the feature of both schemes and show that the new schemes can withstand conspiracy attacks without attaching a secret number and...

article

Fast Marching and Runge–Kutta Based Method for Centreline Extraction of Right Coronary Artery in Human Patients

Hengfei Cui, Desheng Wang, Min Wan, Jun-Mei Zhang, more

Cardiovascular Engineering and Technology > 2016 > 7 > 2 > 159-169

The CT angiography (CTA) is a clinically indicated test for the assessment of coronary luminal stenosis that requires centerline extractions. There is currently no centerline extraction algorithm that is automatic, real-time and very accurate. Therefore, we sought to (i) develop a hybrid approach by incorporating fast marching and Runge–Kutta based methods for the extraction of coronary artery centerlines...

article

Correcting motion in multiplanar cardiac magnetic resonance images

Min Wan, Wei Huang, Jun-Mei Zhang, Xiaodan Zhao, more

BioMedical Engineering OnLine > 2016 > 15 > 1 > 1-16

Background Misalignment in cardiac magnetic resonance (CMR) images can adversely affect three-dimensional left ventricle modelling and downstream quantitative analysis. Currently, there are two types of approaches for dealing with realignment and motion distortion problems, one image based and the other geometry based. Image-based approaches are limited by the inherent non-homogeneity and anisotropy...

chapter

Automatic localization of mitral valve orifice in three-dimensional left cardiac model

Min Wan, Liang Zhong, Jun-Mei Zhang, Xiaodan Zhao, more

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) > 6540 - 6543

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

This study proposes a novel method to localize the mitral valve orifice in the three-dimensional left cardiac model reconstructed from Cardiac Magnetic Resonance (CMR) images. After acquiring both short axis and long axis CMR images, endocardium contours were delineated on all images while additional six points were marked to identify the mitral valve orifice on three long axis images. Contours from...

article

Hemodynamic analysis of patient‐specific coronary artery tree

Jun‐Mei Zhang, Tong Luo, Swee Yaw Tan, Aileen Mae Lomarda, more

International Journal for Numerical Methods in Biomedical Engineering > 31 > 4 > n/a - n/a

Local hemodynamic parameters, such as wall shear stress (WSS), oscillatory shear index and relative resident time (RRT), have been linked to coronary plaque initiation and progression. In this study, a left coronary artery tree model was reconstructed from computed tomography angiography images of a patient with multiple stenoses. The geometry of the coronary artery tree model was virtually restored...

chapter

Coronary artery segmentation via Hessian filter and curve-skeleton extraction

Hengfei Cui, Desheng Wang, Min Wan, Jun-Mei Zhang, more

2014 IEEE Conference on Biomedical Engineering and Sciences (IECBES) > 93 - 98

2014 IEEE Conference on Biomedical Engineering and Sciences (IECBES)

Precise coronary artery segmentation is a prerequisite for quantitatively assessing the severity of coronary artery stenosis. Extracting the centre line of the 3D volumetric coronary artery tree, also named as 3D skeletonization, plays an important role in identify the variations of cross-sectional profile. Typically there are three skeletonization methods, viz. distance transformation, Voronoi method...

chapter

Patient-specific blood flows and vortex formations in patients with hypertrophic cardiomyopathy using computational fluid dynamics

Boyang Su, Jun-Mei Zhang, Hak Chiaw Tang, Min Wan, more

2014 IEEE Conference on Biomedical Engineering and Sciences (IECBES) > 276 - 280

2014 IEEE Conference on Biomedical Engineering and Sciences (IECBES)

Hypertrophic cardiomyopathy (HCM) is a relatively common genetic cardiac disorder in which a portion of the myocardium becomes hypertrophied. Dynamic left ventricle outflow tract obstruction is present and associated with worsened symptom severity and disease progression. However, its mechanism is still not fully understood, and the complex interaction between the thickened ventricular wall and altered...

chapter

Evaluation of atrioventricular junction velocity by orthogonal polynomial fitting from cine magnetic resonance imaging and comparison with tissue Doppler Echocardiography

Xiaodan Zhao, Ru San Tan, Jia Ing Wong, Fei Qiong Huang, more

2014 IEEE Conference on Biomedical Engineering and Sciences (IECBES) > 271 - 275

2014 IEEE Conference on Biomedical Engineering and Sciences (IECBES)

This study was carried out to (i) provide the methodology for determining atrio-ventricular junction (AVJ) motion from cine magnetic resonance imaging (MRI), and (ii) compare its derived velocities (i.e., myocardial systolic velocity Sm1 and early diastolic velocity Em) with tissue Doppler echocardiography in normal healthy subjects. Both cine MRI and Echocardiography were performed in 23 normal healthy...

chapter

Characterization and quantification of curvature using independent coordinates method in the human left ventricle by magnetic resonance imaging to identify the morphology subtype of hypertrophy cardiomyopathy

Liang Zhong, Xiaodan Zhao, Min Wan, Jun-Mei Zhang, more

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society > 5619 - 5622

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

The patterns of ventricular hypertrophy are critical determinants of blood flow and function, but are variable. Therefore, it is clinically relevant to assess the hypertrophic shape patterns to better characterize and identify the morphological subtypes. We proposed and developed an independent coordinates method (ICM) to quantify the regional shape of the left ventricle in terms of curvature. 19...

chapter

Left ventricular regional shape dynamics analysis by three-dimensional cardiac magnetic resonance imaging associated with left ventricular function in first-time myocardial infarction patients

Min Wan, Teo Soo Kng, Xulei Yang, Jun-Mei Zhang, more

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society > 5113 - 5116

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

Geometric remodelling of the left ventricle (LV) following myocardial infarction reflects on the geometric characteristics directly. This study focuses on a potential index based on curvedness. Nine consecutive normal volunteers and thirty consecutive myocardial infarction patients underwent MRI scan (twenty-seven patients had follow-up scan). Short-axis cine images of all cases were delineated. Three...

chapter

Graph-cuts based reconstructing patient specific right ventricle: First human study

Liang Zhong, Min Wan, Yi Su, Soo Kng Teo, more

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society > 6770 - 6773

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

Right ventricular (RV) function is increasingly recognized to play an important role in the clinical status and long-term outcome in patients with congenital heart disease as well as ischemic cardiomyopathy with left ventricular dysfunction. However, quantification of RV characteristics and function are still challenging due to its complex morphology and its thin wall with coarse trabeculations. To...

article

Perspective on CFD studies of coronary artery disease lesions and hemodynamics: A review

Jun‐Mei Zhang, Liang Zhong, Boyang Su, Min Wan, more

International Journal for Numerical Methods in Biomedical Engineering > 30 > 6 > 659 - 680

Coronary artery disease (CAD) is the most common cardiovascular disease. Early diagnosis of CAD's physiological significance is of utmost importance for guiding individualized risk‐tailored treatment strategies. In this paper, we first review the state‐of‐the‐art clinical diagnostic indices to quantify the severity of CAD and the associated invasive and noninvasive imaging technologies in order to...

article

Numerical simulation of patient-specific left ventricular model with both mitral and aortic valves by FSI approach

Boyang Su, Liang Zhong, Xi-Kun Wang, Jun-Mei Zhang, more

Computer Methods and Programs in Biomedicine > 2014 > 113 > 2 > 474-482

Intraventricular flow is important in understanding left ventricular function; however, relevant numerical simulations are limited, especially when heart valve function is taken into account. In this study, intraventricular flow in a patient-specific left ventricle has been modelled in two-dimension (2D) with both mitral and aortic valves integrated. The arbitrary Lagrangian–Eulerian (ALE) approach...

chapter

Effects of Stenosis on the Porcine Left Anterior Descending Arterial Tree

Liang Zhong, Boyang Su, Jun-Mei Zhang, Yunlong Huo, more

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) > 3869 - 3872

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

In this study, hemodynamics in the normal and diseased left anterior descending (LAD) arterial trees were compared to estimate the effects of stenosis on the flow rate distribution, detailed flow field and wall shear stress (WSS) distributions on both transient and steady flow conditions. The anatomical model was reconstructed from computed tomography (CT) images of a normal porcine heart. Stenosis...

chapter

Area stenosis associated with non-invasive fractional flow reserve obtained from coronary CT images

Jun-Mei Zhang, Tong Luo, Yunlong Huo, Min Wan, more

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) > 3865 - 3868

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

Fractional flow reserve (FFR) determined by invasive angiography is the gold standard to assess the severity of coronary artery disease (CAD). FFRCT can be obtained non-invasively by combining computed tomography (CT) images and Computational Fluid Dynamics (CFD) method. In this study, FFR_CT was computed for 6 models of patient-specific left coronary artery trees reconstructed from CT images. A total...

chapter

FSI simulation of intra-ventricular flow in patient-specific ventricular model with both mitral and aortic valves

Liang Zhong, Boyang Su, Jun-Mei Zhang, Hwa Liang Leo, more

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) > 703 - 706

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

Investigating the intra-ventricular flow is the most important to understand the left ventricular function. In this study, we proposed a fluid-structure interaction (FSI) approach to simulate the blood flow in patient-specific model by combining both mitral and aortic valves. To accommodate the large mesh deformation, moving arbitrary Lagrangian-Eulerian (ALE) meshes were used for moving ventricular...

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INFONA - science communication portal

Search results for: Jun‐Mei Zhang

Paraneoplastic pemphigus misdiagnosed as juvenile dermatomyositis: A case report

Comparison of different sedatives in children before general anaesthesia for selective surgery: A network meta‐analysis

Analysis of three-dimensional endocardial and epicardial strains from cardiac magnetic resonance in healthy subjects and patients with hypertrophic cardiomyopathy

Cardiac MRI based numerical modeling of left ventricular fluid dynamics with mitral valve incorporated

Group-Oriented (t, n) Threshold Digital Signature Schemes with Traceable Signers

Fast Marching and Runge–Kutta Based Method for Centreline Extraction of Right Coronary Artery in Human Patients

Correcting motion in multiplanar cardiac magnetic resonance images

Automatic localization of mitral valve orifice in three-dimensional left cardiac model

Hemodynamic analysis of patient‐specific coronary artery tree

Coronary artery segmentation via Hessian filter and curve-skeleton extraction

Patient-specific blood flows and vortex formations in patients with hypertrophic cardiomyopathy using computational fluid dynamics

Evaluation of atrioventricular junction velocity by orthogonal polynomial fitting from cine magnetic resonance imaging and comparison with tissue Doppler Echocardiography

Characterization and quantification of curvature using independent coordinates method in the human left ventricle by magnetic resonance imaging to identify the morphology subtype of hypertrophy cardiomyopathy

Left ventricular regional shape dynamics analysis by three-dimensional cardiac magnetic resonance imaging associated with left ventricular function in first-time myocardial infarction patients

Graph-cuts based reconstructing patient specific right ventricle: First human study

Perspective on CFD studies of coronary artery disease lesions and hemodynamics: A review

Numerical simulation of patient-specific left ventricular model with both mitral and aortic valves by FSI approach

Effects of Stenosis on the Porcine Left Anterior Descending Arterial Tree

Area stenosis associated with non-invasive fractional flow reserve obtained from coronary CT images

FSI simulation of intra-ventricular flow in patient-specific ventricular model with both mitral and aortic valves

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