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BackgroundIncidences of primary cutaneous melanoma (CM) have risen over the last few decades, mainly among populations of White European extraction. Some risk factors for melanoma have been clearly established, but other potential risk factors, such as exposure to pesticides, are currently under study.
MethodsA case–control study on melanoma was conducted during 2012 and 2013 at three dermatological...
AimIn this study, we investigated the regulatory network of the key and rate‐limiting enzyme of cholesterol biosynthetic pathway, the 3‐hydroxy 3‐methylglutaryl coenzyme A reductase (HMGR) in different brain regions, to add new insight about lipid metabolism and physiology in the central nervous system (CNS).
MethodsHMGR levels and activation state and the proteins involved in the enzyme regulatory...
This paper presents the OOTN - ontology for optical transport networks: a computational ontology proposal for optical transport networks based on the ITU-T G.805 and G.872 recommendations. It shows the most relevant issues found during the modeling process and presents a case study where the classical concepts of VTD and RWA applications have been mapped to OOTN.
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