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A central goal of neuroscience is to understand how populations of neurons coordinate and cooperate in order to give rise to perception, cognition, and action. Nonhuman primates (NHPs) are an attractive model with which to understand these mechanisms in humans, primarily due to the strong homology of their brains and the cognitively sophisticated behaviors they can be trained to perform. Using electrode...
Optical functional imaging methods such as calcium imaging have become a powerful tool for investigating neural activity in-vivo. Here, we present a design for a titanium implantable chamber with transparent silicone artificial dura which enables two-photon calcium imaging in non-human primates. This chamber accommodates imaging with high numerical aperture multiphoton objective lenses, and remains...
This paper presents a supervised learning approach to improving the autonomous mobility of wheeled robots through sensing the robot’s interaction with terrain ‘underfoot.’ Mobility characterization is cast as a hierarchical task, in which pre-immobilization detection is achieved using support vector machines in time to prevent full immobilization, and if a pre-immobilization condition is detected,...
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