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Background
Aetiological diagnosis in non‐syndromic intellectual disability (NSID) still poses a diagnostic challenge to clinicians.
Methods
Screening is currently achieved by chromosomal microarrays followed by whole‐exome sequencing (WES). In search for the aetiological yield of WES in patients with NSID, 59 unrelated patients were studied.
Results
Among the 59 patients, 44 (74.6%) were from...
We present efficient and accurate solutions of scattering problems involving dense discretizations with respect to wavelength. Recently developed potential integral equations (PIEs) for stable solutions of low-frequency problems are used to formulate such challenging problems, where the electric current density and magnetic vector potential are defined as unknowns. For solving problems discretized...
We consider the accuracy and efficiency of surface integral equations, when they are used to formulate electromagnetic problems involving plasmonic objects at optical frequencies. Investigations on the iterative solutions of scattering problems with the multilevel fast multipole algorithm show that the conventional formulations, especially the state-of-the-art integral equations, can significantly...
We present an electromagnetic optimization environment based on full-wave solutions via surface integral equations and the multilevel fast multipole algorithm (MLFMA). Optimizations are performed by using genetic algorithms, while the required trials are performed accurately via MLFMA. The developed mechanism can handle many different operations, such as portion moving/removing, rotation, and gap...
A broadband implementation of the multilevel fast multipole algorithm is developed and employed to solve multiscale problems involving large objects with small details and discretizations. Despite its limited accuracy, the proposed scaled diagonalization enables stable computations of electromagnetic interactions at arbitrary short distances with respect to wavelength. The effectiveness of the developed...
We present an approximate diagonalization of the three-dimensional Green's function for straightforward broadband implementations of the multilevel fast multipole algorithm. The diagonalization is based on the use of scaled spherical functions and plane waves, leading to approximate but stable expansions for arbitrarily short distances with respect to wavelength. Despite its limited accuracy, the...
We present generalized hybrid surface-integral-equation formulations for three-dimensional conductors with arbitrary shapes. The proposed formulations are based on flexible applications of the electric-field integral equation and the magnetic-field integral equation with varying combinations on different regions of the given objects. As a proof of concept, we demonstrate hybrid formulations using...
We present computationally intensive electromagnetic analysis of metamaterials involving deformed nanowires. Random deformations are introduced to modify perfect nanowires in order to investigate the effect of geometric deviations on scattering properties of optical meta-materials. Numerical simulations of realistic structures of finite extent are performed accurately and efficiently using a rigorous...
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