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This paper presents a chip containing a flexible scaffold which facilitates the construction of tissues with different shapes. The chip, entirely made of Polydimethylsiloxane (PDMS), has 2 main components including actuator and channel layers. The actuator layer consists of a 6×6 array of membrane actuators, with round shapes. The channel layer has a single layered structure due to the simplicity...
The unique geometry of toroidal cellular aggregate has caught much attention during last few years due to its variety of applications in tissue engineering. For example, the micro lumen of connected toroidal aggregates enables a communication channel for vascularization within complex cellular constructs. This channel significantly helps preventing the cell death, due to the lack of nutrients. Furthermore,...
This paper presents a flexible microscaffold driven by a thermal latch valve, which helps meet the necessity of engineered tissues with different structures for engineered organ assembly. Unlike the conventional approach, which normally utilizes a fixed scaffold, our flexible microscaffold offers many temporary scaffolds as needed. It consists of a 3×3 microactuator array with a diameter of 500 μm...
We present the novel framework of knowledge construction (ICC: Independent Co-occurring based Construction) based on co-occurrence relations of objects. We compare its characteristics with that of general approach (DCC: Dependent Co-occurring based Construction) in various construction aspects: variations of trained probability values, percentage differences (probability value and priority ranking...
This paper presents a flexible microscaffold to facilitate the fabrication of different cellular constructs which could be used as the building units for the construction of a larger tissue with a complex structure. The device consists of a 6×6 array of membrane actuators, made of Polydimethylsiloxane. The superiority of membrane actuators helps preventing the leakage of culture medium and allows...
Assembling engineered tissues at the mesoscale into an engineered organ has specially attracted our attention since engineered organ usually has a very complex structure and cannot be fabricated simply by using a fixed scaffold. The fabrication of these composite tissues is, however, difficult since many different scaffolds are required. The flexible microsaffold, called “changeable cell culture (C...
Object search in unknown human environment by utilizing Object Co-occurrence Graph (OCG) is presented. In our approach, OCG which represents co-occurrence relations between objects is employed as robot's knowledge. Since direct search that solely relies on the finding of target object in each scene may face some difficulties such as insufficient image's resolution, illumination change, or occlusion...
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