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Recent advances in flow-based microfluidic biochips have enabled the emergence of lab-on-a-chip devices for bimolecular recognition and point-of-care disease diagnostics. However, the adoption of flow-based biochips is hampered today by the lack of computer-aided design tools. Manual design procedures not only delay product development but they also inhibit the exploitation of the design complexity...
Digital micro fluidic biochips have become one of the most promising technologies in many biomedical fields. In a digital micro fluidic biochip, a group of (adjacent) cells in the micro fluidic array can be configured to work as storage, functional operations, as well as for transporting fluid droplets dynamically. There has been proposed a very efficient Integer Linear Programming (ILP)-based method...
Digital microfluidics is viewed as one of the most promising technologies for biomedical experiments. Digital microfluidic biochips are often used today for applications such as point-of-care health assessment, drug discovery, and air-quality monitoring. Therefore, such devices must be adequately tested after manufacturing to guarantee the correctness of the biomedical experiments. Previous test methods...
As in the case of VLSI circuits, digital microfluidic biochips must be adequately tested after manufacturing to guarantee the correctness of the biomedical experiments. In this work, we propose an efficient test method for digital microfluidic biochips. In contrast to related prior work, the proposed test method is not only able to cover all chip defects but also applicable to arbitrary chip layouts...
Digital microfluidic biochips have become one of the most promising technologies for biomedical experiments. In modern microfluidic technology, reducing the number of independent control pins that reflects most of the fabrication cost, power consumption, and reliability of a microfluidic system, is a key challenge for every digital microfluidic biochip design. However, all the previous chip designs...
A digital micro fluidic biochip (DMFB) is an attractive platform for immunoassays, point-of-care clinical diagnostics, DNA sequencing, and other laboratory procedures in biochemistry. Effective testing methods are required to ensure robust DMFB operation and high confidence in the outcome of biochemical experiments. Prior work on DMFB testing does not address the problem of designing the test to minimize...
Digital microfluidic biochips have become one of the most promising technologies for biomedical experiments. In modern microfluidic technology, reducing the number of independent control pins that reflects most of the fabrication cost, power consumption and reliability of a microfluidic system, is a key challenge for every digital microfluidic biochip design. However, all the previous chip designs...
Sample preparation, which is a front-end process to produce droplets of the desired target concentrations from input reagents, plays a pivotal role in every assay, laboratory, and application in biomedical engineering and life science. The consumption of sample/buffer/waste is usually used to evaluate the effectiveness of a sample preparation process. In this paper, for the first time, we present...
Recent advantages in flow-based microfluidic biochips have enabled the emergence of lab-on-a-chip devices for bimolecular recognition and point-of-care disease diagnostics. However, the adoption of flow-based biochips is hampered today by the lack of computer-aided design tools. Manual design procedures not only delay product development but they also inhibit the exploitation of the design complexity...
Microfluidic biochips have been recently proposed to integrate all the necessary functions for biochemical analysis. There are several types of microfluidic biochips; among them there has been a great interest in flow-based microfluidic biochips, in which the flow of liquid is manipulated using integrated microvalves. By combining several microvalves, more complex resource units such as micropumps,...
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