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In this paper a new tool simultaneously to detect viscoelastic and dielectric properties of human fluids is presented. Therefore, one-port SAW resonators (SAW … surface acoustic wave) with fundamental modes of 85, 170 und 340 MHz were developed. Shear horizontal polarized surface acoustic waves (SH-SAW) are used to detect the viscoelastic properties of coagulating blood and blood plasma samples. The...
In this paper a new tool to assess viscoelastic and dielectric properties of human fluids is presented. Shear horizontal polarized surface acoustic waves (SH-SAW) are used to detect the viscoelastic properties of coagulating blood and blood plasma samples. One-port SAW resonators, with fundamental modes of 85, 170 und 340 MHz were developed. Additionally, their electrode structures can be used simultaneously...
In this paper a new tool to assess viscoelastic and dielectric properties of biological samples is presented. Shear horizontal polarized surface acoustic waves (SH-SAW) are used to detect the viscoelastic properties of the extracellular matrix (ECM) expelled by adhering fibroblast cell cultures. Therefore a one-port SAW resonator, with a fundamental mode of 85 MHz was developed. Its electrode structure...
In this paper a new tool to assess viscoelastic and dielectric properties of biological samples is presented. Shear horizontal polarized surface acoustic waves (SH-SAW) are used to detect the viscoelastic properties of biological samples. Therefore a one-port SAW resonator, with a fundamental mode of 85 MHz was developed. Its electrode structure can be used simultaneously to detect the dielectric...
In this study, a new way of investigating a surface acoustic wave (SAW) based sensor device is reported. For that, SAW sensors with a fundamental mode of about 85 MHz and a metallization of gold were developed. Realized as one port resonators, these sensors allow the continuous detection of electric and viscoelastic properties of the same living cell culture in one measurement step. For obtaining...
In this paper preliminary results for the detection of the cell adhesion process with shear-horizontal polarized surface acoustic wave devices (SH-SAW) are presented. The murine fibroblast cell line L929 was investigated. Therefore a special measurement setup was developed. It enables us to perform long term measurements at stable ambient conditions. Different amounts of cells where seeded. According...
Using a one-dimensional approach the electric admittance |Y| of a quartz crystal microbalance (QCM) is calculated as a function of frequency depending on material properties as well as the acoustic impedance of an arbitrary loading. Several solutions for the shift of specific frequencies are derived and methods presented to either suppress or compute the influence of parasitic effects. Measurements...
In our previous work we demonstrated the general suitability of surface and bulk acoustic wave (SAW and BAW) structures for recording the continuous change of fluidic behavior in the course of blood coagulation processes [Guhr et al.,2005]. Special advantage can be taken from the direct impact of fluid consistence on SAW and BAW device parameters (e. g. resonator frequency, quality factor, impedance)...
The purpose of the present paper is to show that thrombelastography can be carried out by means of a quartz crystal microbalance (QCM) also known as a thickness shear mode resonator (TSM). A 9 MHz AT cut quartz was taken for the characterization of whole blood samples from healthy donors. To initiate fibrinolysis effects a special agent was used. The coagulation process was measured by monitoring...
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