Search results for: Wen Ding

Items from 1 to 20 out of 278 results

article

Down‐expression of Foxj1 on airway epithelium with impaired cilia architecture in non‐cystic fibrosis bronchiectasis implies disease severity

Xiao‐Ling Zou, Hai‐Ling Yang, Wen‐Wen Ding, Hai‐Ke Li, more

The Clinical Respiratory Journal > 17 > 5 > 405 - 413

Introduction The pathogenesis of non‐cystic fibrosis bronchiectasis has not been clearly clarified. This study aimed to investigate the expression of ciliary regulating protein forkhead box protein j1 (Foxj1) on airway epithelium in non‐cystic fibrosis bronchiectasis and its association with airway cilia structure disorder and disease severity. Methods Lung tissue sections excised from 47 patients...

article

Insights into peptide profiling of sturgeon myofibrillar proteins with low temperature vacuum heating

Dan‐dan Jiang, Shi‐ke Shen, Wen‐tao Yu, Qian‐yun Bu, more

Journal of the Science of Food and Agriculture > 103 > 6 > 2858 - 2866

BACKGROUND Protein oxidation during food processing causes changes in the balance of protein–molecular interactions and protein–water interactions, ultimately leading to protein denaturation, which results in the loss of a range of functional properties. Therefore, how to control the oxidative modification of proteins during processing has been the focus of research. RESULTS In the present study,...

article

Mechanisms of efferocytosis in determining inflammation resolution: Therapeutic potential and the association with cardiovascular disease

Jishou Zhang, Wen Ding, Mengmeng Zhao, Jianfang Liu, more

British Journal of Pharmacology > 179 > 23 > 5151 - 5171

Efferocytosis is defined as the clearance of apoptotic cells (ACs) in physiological and pathological states and is performed by efferocytes, such as macrophages. Efferocytosis can lead to the resolution of inflammation and restore tissue homoeostasis; however, the mechanisms of efferocytosis in determining inflammation resolution are still not completely understood, and the effects of efferocytosis...

article

Optimization of initial dose regimen of tacrolimus in paediatric lung transplant recipients based on Monte Carlo simulation

Dong‐Dong Wang, Yu‐Qing Mei, Lan Yang, Ke‐Wen Ding, more

Journal of Clinical Pharmacy and Therapeutics > 47 > 10 > 1659 - 1666

What is Known and Objectives The initial tacrolimus dose regimen in paediatric lung transplant recipients is unknown. The present study optimized the initial tacrolimus dose regimen for paediatric lung transplant recipients. Methods This study was based on a published population pharmacokinetic model of tacrolimus in lung transplant recipients and used Monte Carlo simulations to recommend an initial...

article

Monitoring the lipid oxidation and flavor of Russian sturgeon fillets treated with low temperature vacuum heating: formation and relationship

Shi‐Ke Shen, Zheng‐Yang Wu, Yue‐Wen Chen, Xiu‐Ping Dong, more

Journal of the Science of Food and Agriculture > 102 > 11 > 4609 - 4619

BACKGROUND Sturgeon is one of the most precious fish resources worldwide. Low temperature vacuum heating (LTVH) has been confirmed as a good way of maintaining food quality. However, there is a lack of in‐depth studies assessing the impact of LTVH on lipid oxidation and flavor formation. RESULTS The present study compared the effect of LTVH and traditional cooking on lipid oxidation and flavor...

article

Fast and sensitive graphene oxide‐DNAzyme‐based biosensor for Vibrio alginolyticus detection

Xueqing Tian, Jinfei Hu, Tong Wei, Wen Ding, more

Journal of Fish Diseases > 45 > 5 > 687 - 697

DNAzymes have been widely and effectively used for the detection of pathogenic bacteria, which pose a serious public health threat. However, the rapid and cost‐effective detection of such bacteria remains a major challenge. In this study, we successfully selected Vibrio alginolyticus‐specific DNAzymes. The activity of the candidates was assessed via fluorescence intensity and gel electrophoresis. The...

article

Geomorphologic study of human tooth root surfaces following simulated avulsion by scanning electron microscopy

Qian‐Wen Ding, Mei Lin, Xin Zhang, Yi Gong

Dental Traumatology > 37 > 3 > 457 - 463

Background/Aims Tooth avulsion is the most severe traumatic tooth injury. Immediate replantation after avulsion provides the highest success rate, whereas delayed replantation with dehydration for >1 h always results in ankylosis, replacement resorption, and eventual tooth loss. The aim of this study was to investigate the geomorphologic change of ultrastructure on tooth root surfaces due to dehydration...

article

Diversity and functional analysis of Chinese bumblebee gut microbiota reveal the metabolic niche and antibiotic resistance variation of Gilliamella

Zi‐Jing Zhang, Ming‐Fei Huang, Li‐Fei Qiu, Rui‐Hao Song, more

Insect Science > 28 > 2 > 302 - 314

Bumblebees play an important role in maintaining the balance of natural and agricultural ecosystems, and the characteristic gut microbiota of bumblebees exhibit significant mutualistic functions. China has the highest diversity of bumblebees; however, gut microbiota of Chinese bumblebees have mostly been investigated through culture‐independent studies. Here, we analyzed the gut communities of bumblebees...

article

Luminescence Activity Decreases When v‐coelenterazine Replaces Coelenterazine in Calcium‐Regulated Photoprotein—A Theoretical and Experimental Study

Bo‐Wen Ding, Elena V. Eremeeva, Eugene S. Vysotski, Ya‐Jun Liu

Photochemistry and Photobiology > 96 > 5 > 1047 - 1060

Calcium‐regulated photoproteins are found in at least five phyla of organisms. The light emitted by those photoproteins can be tuned by mutating the photoprotein and/or by modifying the substrate coelenterazine (CTZ). Thirty years ago, Shimomura observed that the luminescence activity of aequorin was dramatically reduced when the substrate CTZ was replaced by its analog v‐CTZ. The latter is formed...

article

RPB5‐Mediating Protein Promotes Cholangiocarcinoma Tumorigenesis and Drug Resistance by Competing With NRF2 for KEAP1 Binding

Zheng‐Hua Wan, Tian‐Yi Jiang, Yuan‐Yuan Shi, Yu‐Fei Pan, more

Hepatology > 71 > 6 > 2005 - 2022

Background and Aims Cancer cell survival depends on the balance between reactive oxygen species production and scavenging, which is regulated primarily by NRF2 during tumorigenesis. Here, we demonstrate that deletion of RBP5‐mediating protein (RMP) in an autonomous mouse model of intrahepatic cholangiocarcinoma (ICC) delays tumor progression. Approach and Results RMP‐overexpressing tumor cells...

article

Ultrasound-promoted synthesis of γ-graphyne for supercapacitor and photoelectrochemical applications

Wen Ding, Mingxuan Sun, Zihan Zhang, Xiaojing Lin, more

Ultrasonics Sonochemistry > 2020 > 61 > C

As a novel type of carbon materials, graphynes possesses the merits of high carrier mobility and large surface areas, etc. However, to date, the main research of graphynes is focused on theoretical calculation whereas few strategies have been reported for the fabrication of graphynes. In this work, a facile method named ultrasound-promoted synthesis was developed to fabricate γ-graphyne using PhBr...

article

Global warming and artificial shorelines reshape seashore biogeography

Wei Wang, Jie Wang, Francis M. P. Choi, Ping Ding, more

Global Ecology and Biogeography > 29 > 2 > 220 - 231

Aim Rapid anthropogenic warming coupled with changes in land use is altering the distributions of species, with consequences for ecosystem functioning and services. It is crucial to evaluate species range shifts based on understanding of the interaction of temperature with non‐climatic factors such as habitat availability and dispersal potential. Here, we aim to investigate roles of environmental...

article

Front Cover

Wei Wang, Jie Wang, Francis M. P. Choi, Ping Ding, more

Global Ecology and Biogeography > 29 > 2 > i - i

The cover image is based on the Original Article* Global warming and artificial shorelines reshape seashore biogeography by YUN‐WEI DONG** et al., https://doi.org/10.1111/geb.13019.***

article

Thioredoxin peroxidase secreted by Echinococcus granulosus (sensu stricto) promotes the alternative activation of macrophages via PI3K/AKT/mTOR pathway

Hui Wang, Chuan-Shan Zhang, Bin-Bin Fang, Zhi-De Li, more

Parasites & Vectors > 2019 > 12 > 1 > 1-13

Background Larvae of Echinococcus granulosus (sensu lato) dwell in host organs for a long time but elicit only a mild inflammatory response, which indicates that the resolution of host inflammation is necessary for parasite survival. The recruitment of alternatively activated macrophages (AAMs) has been observed in a variety of helminth infections, and emerging evidence indicates that AAMs are critical...

article

An organic polymer monolith modified with an amino acid ionic liquid and graphene oxide for use in capillary electrochromatography: application to the separation of amino acids, β-blockers, and nucleotides

Shiyuan Zhao, Tao Yu, Yingxiang Du, Xiaodong Sun, more

Microchimica Acta > 2019 > 186 > 9 > 1-10

The preparation of an organic polymer monolithic column modified with an amino acid ionic liquid and graphene oxide (AAIL-GO) and its application to capillary electrochromatography (CEC) was described. The AAIL tetramethylammonium-L-arginine was bonded to a monolithic column that was previously modified with graphene oxide by using an hydrochloride/N-hydroxysuccinimide coupling reaction. The morphology...

article

Correction to: Metal organic framework HKUST-1 modified with carboxymethyl-β-cyclodextrin for use in improved open tubular capillary electrochromatographic enantioseparation of five basic drugs

Xiaodong Sun, Tao Yu, Yingxiang Du, Wen Ding, more

Microchimica Acta > 2019 > 186 > 9 > 1-1

The published version of this article, unfortunately, contains error. The author found out that the given name interchanged with the family name. The second author’s family name should be “Yu” and the first name should be “Tao”. Given in this article is the correct author name.

article

Chemical Constituents of the Essential Oil Extracted from Phoebe bournei

Qi Zhang, Liping Ning, Wen Ding, Huizi Xing, more

Chemistry of Natural Compounds > 2019 > 55 > 4 > 754-755

Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2019, pp. 643–644.

article

Metal organic framework HKUST-1 modified with carboxymethyl-β-cyclodextrin for use in improved open tubular capillary electrochromatographic enantioseparation of five basic drugs

Xiaodong Sun, Yu Tao, Yingxiang Du, Wen Ding, more

Microchimica Acta > 2019 > 186 > 7 > 1-8

This work shows that the metal organic framework (MOF) HKUST-1 of type Cu₃(BTC)₂ (also referred to as MOF-199; a face-centered-cubic MOF containing nanochannels) is a most viable coating for use in enantioseparation in capillary electrochromatography (CEC). A HKUST-1 modified capillary was prepared and characterized by scanning electron microscopy, transmission electron microscopy, Fourier transform...

article

Comprehensive mutation detection of BRCA1/2 genes reveals large genomic rearrangements contribute to hereditary breast and ovarian cancer in Chinese women

Wen-Ming Cao, Ya-Bing Zheng, Yun Gao, Xiao-Wen Ding, more

BMC Cancer > 2019 > 19 > 1 > 1-8

Background Mutated BRCA1/2 genes are associated with hereditary breast and ovarian cancer (HBOC). So far most of the identified BRCA1/2 pathogenic variants are single nucleotide variants (SNVs) or insertions/deletions (Indels). However, large genomic rearrangements (LGRs) such as copy number variants (CNVs) are also playing an important role in HBOC predisposition. Their frequency and spectrum have...

article

Misassembly of long reads undermines de novo-assembled ethnicity-specific genomes: validation in a Chinese Han population

Zhibiao Mai, Wanting Liu, Wen Ding, Gong Zhang

Human Genetics > 2019 > 138 > 7 > 757-769

An ethnicity is characterized by genomic fragments, single nucleotide polymorphisms (SNPs), and structural variations specific to it. However, the widely used ‘standard human reference genome’ GRCh37/38 is based on Caucasians. Therefore, de novo-assembled reference genomes for specific ethnicities would have advantages for genetics and precision medicine applications, especially with the long-read...

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INFONA - science communication portal

Search results for: Wen Ding

Down‐expression of Foxj1 on airway epithelium with impaired cilia architecture in non‐cystic fibrosis bronchiectasis implies disease severity

Insights into peptide profiling of sturgeon myofibrillar proteins with low temperature vacuum heating

Mechanisms of efferocytosis in determining inflammation resolution: Therapeutic potential and the association with cardiovascular disease

Optimization of initial dose regimen of tacrolimus in paediatric lung transplant recipients based on Monte Carlo simulation

Monitoring the lipid oxidation and flavor of Russian sturgeon fillets treated with low temperature vacuum heating: formation and relationship

Fast and sensitive graphene oxide‐DNAzyme‐based biosensor for Vibrio alginolyticus detection

Geomorphologic study of human tooth root surfaces following simulated avulsion by scanning electron microscopy

Diversity and functional analysis of Chinese bumblebee gut microbiota reveal the metabolic niche and antibiotic resistance variation of Gilliamella

Luminescence Activity Decreases When v‐coelenterazine Replaces Coelenterazine in Calcium‐Regulated Photoprotein—A Theoretical and Experimental Study

RPB5‐Mediating Protein Promotes Cholangiocarcinoma Tumorigenesis and Drug Resistance by Competing With NRF2 for KEAP1 Binding

Ultrasound-promoted synthesis of γ-graphyne for supercapacitor and photoelectrochemical applications

Global warming and artificial shorelines reshape seashore biogeography

Front Cover

Thioredoxin peroxidase secreted by Echinococcus granulosus (sensu stricto) promotes the alternative activation of macrophages via PI3K/AKT/mTOR pathway

An organic polymer monolith modified with an amino acid ionic liquid and graphene oxide for use in capillary electrochromatography: application to the separation of amino acids, β-blockers, and nucleotides

Correction to: Metal organic framework HKUST-1 modified with carboxymethyl-β-cyclodextrin for use in improved open tubular capillary electrochromatographic enantioseparation of five basic drugs

Chemical Constituents of the Essential Oil Extracted from Phoebe bournei

Metal organic framework HKUST-1 modified with carboxymethyl-β-cyclodextrin for use in improved open tubular capillary electrochromatographic enantioseparation of five basic drugs

Comprehensive mutation detection of BRCA1/2 genes reveals large genomic rearrangements contribute to hereditary breast and ovarian cancer in Chinese women

Misassembly of long reads undermines de novo-assembled ethnicity-specific genomes: validation in a Chinese Han population

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