Search results for: Wen Ding

Items from 1 to 20 out of 269 results

article

RPB5‐Mediating Protein Promotes Cholangiocarcinoma Tumorigenesis and Drug Resistance by Competing With NRF2 for KEAP1 Binding

Zheng‐Hua Wan, Tian‐Yi Jiang, Yuan‐Yuan Shi, Yu‐Fei Pan, more

Hepatology > 71 > 6 > 2005 - 2022

Background and Aims Cancer cell survival depends on the balance between reactive oxygen species production and scavenging, which is regulated primarily by NRF2 during tumorigenesis. Here, we demonstrate that deletion of RBP5‐mediating protein (RMP) in an autonomous mouse model of intrahepatic cholangiocarcinoma (ICC) delays tumor progression. Approach and Results RMP‐overexpressing tumor cells...

article

Ultrasound-promoted synthesis of γ-graphyne for supercapacitor and photoelectrochemical applications

Wen Ding, Mingxuan Sun, Zihan Zhang, Xiaojing Lin, more

Ultrasonics Sonochemistry > 2020 > 61 > C

As a novel type of carbon materials, graphynes possesses the merits of high carrier mobility and large surface areas, etc. However, to date, the main research of graphynes is focused on theoretical calculation whereas few strategies have been reported for the fabrication of graphynes. In this work, a facile method named ultrasound-promoted synthesis was developed to fabricate γ-graphyne using PhBr...

article

Front Cover

Wei Wang, Jie Wang, Francis M. P. Choi, Ping Ding, more

Global Ecology and Biogeography > 29 > 2 > i - i

The cover image is based on the Original Article* Global warming and artificial shorelines reshape seashore biogeography by YUN‐WEI DONG** et al., https://doi.org/10.1111/geb.13019.***

article

Global warming and artificial shorelines reshape seashore biogeography

Wei Wang, Jie Wang, Francis M. P. Choi, Ping Ding, more

Global Ecology and Biogeography > 29 > 2 > 220 - 231

Aim Rapid anthropogenic warming coupled with changes in land use is altering the distributions of species, with consequences for ecosystem functioning and services. It is crucial to evaluate species range shifts based on understanding of the interaction of temperature with non‐climatic factors such as habitat availability and dispersal potential. Here, we aim to investigate roles of environmental...

article

Thioredoxin peroxidase secreted by Echinococcus granulosus (sensu stricto) promotes the alternative activation of macrophages via PI3K/AKT/mTOR pathway

Hui Wang, Chuan-Shan Zhang, Bin-Bin Fang, Zhi-De Li, more

Parasites & Vectors > 2019 > 12 > 1 > 1-13

Background Larvae of Echinococcus granulosus (sensu lato) dwell in host organs for a long time but elicit only a mild inflammatory response, which indicates that the resolution of host inflammation is necessary for parasite survival. The recruitment of alternatively activated macrophages (AAMs) has been observed in a variety of helminth infections, and emerging evidence indicates that AAMs are critical...

article

An organic polymer monolith modified with an amino acid ionic liquid and graphene oxide for use in capillary electrochromatography: application to the separation of amino acids, β-blockers, and nucleotides

Shiyuan Zhao, Tao Yu, Yingxiang Du, Xiaodong Sun, more

Microchimica Acta > 2019 > 186 > 9 > 1-10

The preparation of an organic polymer monolithic column modified with an amino acid ionic liquid and graphene oxide (AAIL-GO) and its application to capillary electrochromatography (CEC) was described. The AAIL tetramethylammonium-L-arginine was bonded to a monolithic column that was previously modified with graphene oxide by using an hydrochloride/N-hydroxysuccinimide coupling reaction. The morphology...

article

Correction to: Metal organic framework HKUST-1 modified with carboxymethyl-β-cyclodextrin for use in improved open tubular capillary electrochromatographic enantioseparation of five basic drugs

Xiaodong Sun, Tao Yu, Yingxiang Du, Wen Ding, more

Microchimica Acta > 2019 > 186 > 9 > 1-1

The published version of this article, unfortunately, contains error. The author found out that the given name interchanged with the family name. The second author’s family name should be “Yu” and the first name should be “Tao”. Given in this article is the correct author name.

article

Chemical Constituents of the Essential Oil Extracted from Phoebe bournei

Qi Zhang, Liping Ning, Wen Ding, Huizi Xing, more

Chemistry of Natural Compounds > 2019 > 55 > 4 > 754-755

Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2019, pp. 643–644.

article

Metal organic framework HKUST-1 modified with carboxymethyl-β-cyclodextrin for use in improved open tubular capillary electrochromatographic enantioseparation of five basic drugs

Xiaodong Sun, Yu Tao, Yingxiang Du, Wen Ding, more

Microchimica Acta > 2019 > 186 > 7 > 1-8

This work shows that the metal organic framework (MOF) HKUST-1 of type Cu₃(BTC)₂ (also referred to as MOF-199; a face-centered-cubic MOF containing nanochannels) is a most viable coating for use in enantioseparation in capillary electrochromatography (CEC). A HKUST-1 modified capillary was prepared and characterized by scanning electron microscopy, transmission electron microscopy, Fourier transform...

article

Comprehensive mutation detection of BRCA1/2 genes reveals large genomic rearrangements contribute to hereditary breast and ovarian cancer in Chinese women

Wen-Ming Cao, Ya-Bing Zheng, Yun Gao, Xiao-Wen Ding, more

BMC Cancer > 2019 > 19 > 1 > 1-8

Background Mutated BRCA1/2 genes are associated with hereditary breast and ovarian cancer (HBOC). So far most of the identified BRCA1/2 pathogenic variants are single nucleotide variants (SNVs) or insertions/deletions (Indels). However, large genomic rearrangements (LGRs) such as copy number variants (CNVs) are also playing an important role in HBOC predisposition. Their frequency and spectrum have...

article

Misassembly of long reads undermines de novo-assembled ethnicity-specific genomes: validation in a Chinese Han population

Zhibiao Mai, Wanting Liu, Wen Ding, Gong Zhang

Human Genetics > 2019 > 138 > 7 > 757-769

An ethnicity is characterized by genomic fragments, single nucleotide polymorphisms (SNPs), and structural variations specific to it. However, the widely used ‘standard human reference genome’ GRCh37/38 is based on Caucasians. Therefore, de novo-assembled reference genomes for specific ethnicities would have advantages for genetics and precision medicine applications, especially with the long-read...

article

Evaluation of a noncanonical Cys40‐Cys55 disulfide linkage for stabilization of single‐domain antibodies

Dae Young Kim, Hiba Kandalaft, Greg Hussack, Shalini Raphael, more

Protein Science > 28 > 5 > 881 - 888

Incorporation of noncanonical disulfide linkages into single‐domain antibodies (sdAbs) has been shown to enhance thermostability and other properties. Here, we evaluated the effects of introducing a novel disulfide linkage formed between Cys residues at IMGT positions 40 and 55 on the melting temperatures (T_ms), reversibility of thermal unfolding, solubility, and antigen‐binding affinities of three...

article

Clonality and clonal evolution analysis of paediatric ALL based on B‐cell receptor/T‐cell receptor rearrangement

Ling‐Wen Ding, Kar‐Tong Tan, Qiao‐Yang Sun, Zhen‐Tang Lao, more

British Journal of Haematology > 184 > 5 > 829 - 833

article

Benchmark study of popular density functionals for calculating binding energies of three‐center two‐electron bonds

Cheng‐Xing Cui, Dongdong Xu, Bo‐Wen Ding, Ling‐Bo Qu, more

Journal of Computational Chemistry > 40 > 4 > 657 - 670

Density functional theory (DFT) can be used to study the three‐center two‐electron (3c2e) bonding mode, which is universal in catalysts containing alkaline‐earth (Ae) and boron‐group (Bg) elements. However, because of the delocalization pattern of the 3c2e bond, the wavefunction cannot be accurately described by DFT methods. The calculated energies of Ae and Bg catalysts therefore fluctuate greatly...

article

Rapid diagnosis of Ditylenchus destructor by loop-mediated isothermal amplification assay based on 28S rRNA sequences

Shan-Wen Ding, Si-Hua Yang, Wen-Jia Wu, Hui Xie, more

European Journal of Plant Pathology > 2019 > 153 > 4 > 1165-1175

Ditylenchus destructor is an important plant pathogenic nematode in agricultural production and is listed as a quarantine pest by many countries and regions. Traditional identification depending on morphological characteristics requires taxonomic expertise and is difficult to apply for rapid identification of plant nematode species. Currently, with the development of molecular biology, many novel...

article

Magnetic response in silicene, germanene, and stanene rings with ferromagnetic and antiferromagnetic exchange field

Ning Xu, Jian Wen Ding, Bao Lin Wang, Heng Yi Xu

The European Physical Journal B > 2018 > 91 > 11 > 1-5

Magnetic response properties of silicene, germanene, and stanene rings have been explored. The total magnetic moment of the rings can be modulated by the exchange field. The magnetic moment of the rings can be regulated and keeps the constant valuewithin certain ferromagnetic exchange filed window. Diamagnetism–paramagnetism or paramagnetism–diamagnetism transitions are observed with the increase...

article

Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines

Kar-Tong Tan, Ling-Wen Ding, Qiao-Yang Sun, Zhen-Tang Lao, more

BMC Cancer > 2018 > 18 > 1 > 1-13

Background Clonal VDJ rearrangement of B/T cell receptors (B/TCRs) occurring during B/T lymphocyte development has been used as a marker to track the clonality of B/T cell populations. Methods We systematically profiled the B/T cell receptor repertoire of 936 cancer cell lines across a variety of cancer types as well as 462 Epstein-Barr Virus (EBV) transformed normal B lymphocyte lines using RNA...

article

A Novel Process of Thermal Decomposition of MnO₂ Nanorods

Jia-Xing Song, Xiang Fang, Tao Guo, Feng-Li Bei, more

Russian Journal of Physical Chemistry A > 2018 > 92 > 9 > 1742-1747

The process of thermal decomposition of MnO₂ nanorods was reported in this paper. The MnO₂ nanorods were synthesized via hydrothermal method. The process of their thermal decomposition was studied by thermogravimetry-differential scanning calorimetry (TG-DSC). For the further analysis of the product during thermal decomposition, the MnO₂ nanorods were calcined at 700 and 1000°C in the muffle furnace,...

article

Highly luminescent lanthanide complexes constructed by Bis-tridentate ligand and as sensor for Et2O

Kai Zheng, Li-Wen Ding, Cheng-Hui Zeng

Inorganic Chemistry Communications > 2018 > 95 > C > 95-99

We report the synthesis of mono-nuclear lanthanide complexes [Ln(tppz)(acac)(NO₃)₂]·acac (tppz = 2,3,5,6-tetra-2-pyridinylpyrazine; acac = acetylacetone; Ln³⁺ = Tb³⁺, 1a; Er³⁺, 1b; Y³⁺, 1c), by introducing the bis-tridentate ligand tppz for the first time. These complexes are fully characterized and luminescence properties are investigated in detail. It is interesting to find that 1a has highly luminescent...

article

The c‐MYC–BMI1 axis is essential for SETDB1‐mediated breast tumourigenesis

Jin‐Fen Xiao, Qiao‐Yang Sun, Ling‐Wen Ding, Wenwen Chien, more

The Journal of Pathology > 246 > 1 > 89 - 102

Characterising the activated oncogenic signalling that leads to advanced breast cancer is of clinical importance. Here, we showed that SET domain, bifurcated 1 (SETDB1), a histone H3 lysine 9 methyltransferase, is aberrantly expressed and behaves as an oncogenic driver in breast cancer. SETDB1 enhances c‐MYC and cyclin D1 expression by promoting the internal ribosome entry site (IRES)‐mediated translation...

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INFONA - science communication portal

Search results for: Wen Ding

RPB5‐Mediating Protein Promotes Cholangiocarcinoma Tumorigenesis and Drug Resistance by Competing With NRF2 for KEAP1 Binding

Ultrasound-promoted synthesis of γ-graphyne for supercapacitor and photoelectrochemical applications

Front Cover

Global warming and artificial shorelines reshape seashore biogeography

Thioredoxin peroxidase secreted by Echinococcus granulosus (sensu stricto) promotes the alternative activation of macrophages via PI3K/AKT/mTOR pathway

An organic polymer monolith modified with an amino acid ionic liquid and graphene oxide for use in capillary electrochromatography: application to the separation of amino acids, β-blockers, and nucleotides

Correction to: Metal organic framework HKUST-1 modified with carboxymethyl-β-cyclodextrin for use in improved open tubular capillary electrochromatographic enantioseparation of five basic drugs

Chemical Constituents of the Essential Oil Extracted from Phoebe bournei

Metal organic framework HKUST-1 modified with carboxymethyl-β-cyclodextrin for use in improved open tubular capillary electrochromatographic enantioseparation of five basic drugs

Comprehensive mutation detection of BRCA1/2 genes reveals large genomic rearrangements contribute to hereditary breast and ovarian cancer in Chinese women

Misassembly of long reads undermines de novo-assembled ethnicity-specific genomes: validation in a Chinese Han population

Evaluation of a noncanonical Cys40‐Cys55 disulfide linkage for stabilization of single‐domain antibodies

Clonality and clonal evolution analysis of paediatric ALL based on B‐cell receptor/T‐cell receptor rearrangement

Benchmark study of popular density functionals for calculating binding energies of three‐center two‐electron bonds

Rapid diagnosis of Ditylenchus destructor by loop-mediated isothermal amplification assay based on 28S rRNA sequences

Magnetic response in silicene, germanene, and stanene rings with ferromagnetic and antiferromagnetic exchange field

Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines

A Novel Process of Thermal Decomposition of MnO₂ Nanorods

Highly luminescent lanthanide complexes constructed by Bis-tridentate ligand and as sensor for Et2O

The c‐MYC–BMI1 axis is essential for SETDB1‐mediated breast tumourigenesis

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