Dan-dan Zhu

article

The main driving factors and responses to increase in soil available potassium in the Yangtze River basin over the past 30 years

Dan‐Dan Zhu, Zhi‐Hong Li, Li‐Xuan Guo, Jian‐Wei Lu, more

Land Degradation & Development > 32 > 16 > 4484 - 4493

Intensive crop rotation is one of the main causes of the continued depletion in soil potassium (K) content in the Yangtze River basin (YRB). However, recent studies have shown that soil K content is increasing in the YRB. Therefore, in this study, experimental and statistical data were collected to evaluate the soil K changes caused by K fertilizer application and straw return across the YRB. The...

article

The maximum possible amount of drug in rapidly separating microneedles

Dan Dan Zhu, Xiao Peng Zhang, Chang Bing Shen, Yong Cui, more

Drug Delivery and Translational Research > 2019 > 9 > 6 > 1133-1142

There is an increasing concern on the drug loading capacity of microneedles (MNs) to meet higher drug dosage requirement. The present study describes the fabrication of modified rapidly separating polyvinyl alcohol (PVA)-based MNs (RS-P-MNs) with high drug loading using a mechanical agitation process. The drugs encapsulated within the PVA polymer gel by mechanical agitation served as an encapsulating...

article

Macromol. Rapid Commun. 20/2018

Bo Zhi Chen, Mohammad Ashfaq, Dan Dan Zhu, Xiao Peng Zhang, more

Macromolecular Rapid Communications > 39 > 20 > n/a - n/a

Inside Front Cover: In article number 1800075, Xin Dong Guo and co‐workers design a novel microneedle patch in which the drug‐loaded microneedles are mounted on the corresponding solid microneedle array. These microneedles are fabricated into a “BUCT 60” pattern to celebrate the 60^th anniversary of Beijing University of Chemical Technology.

article

Controlled Delivery of Insulin Using Rapidly Separating Microneedles Fabricated from Genipin‐Crosslinked Gelatin

Bo Zhi Chen, Mohammad Ashfaq, Dan Dan Zhu, Xiao Peng Zhang, more

Macromolecular Rapid Communications > 39 > 20 > n/a - n/a

Rapidly separating genepin‐crosslinked gelatin (RS‐GC) microneedles (MNs) mounted on the polyvinyl alcohol (PVA)‐coated polylactic acid (PLA) MNs (RS‐PGC‐MNs) are fabricated, in which GC‐MNs deliver insulin within the skin and the PLA supporting array is easily separated by the dissolution of the PVA layer. The release of insulin is controlled by utilizing the virtue of genipin as a crosslinking agent...

article

Efficient adsorption separation of xylene isomers using a facilely fabricated cyclodextrin‐based metal–organic framework

Le Chen, Dan‐Dan Zhu, Guo‐Jian Ji, Sheng Yuan, more

Journal of Chemical Technology & Biotechnology > 93 > 10 > 2898 - 2905

Background Metal−organic frameworks (MOFs) are energy‐efficient adsorbents for separating industrial chemical feedstocks. A type of MOF containing an extended porous network of γ‐cyclodextrin (γ‐CD) and alkali metal salts, CD‐MOF, has potential applications in adsorption separation processes in the petrochemical industry. This study aims to present the adsorption efficiency of CD‐MOF‐1 in separating...

article

The role of uric acid in the pathogenesis of diabetic retinopathy based on Notch pathway

Dan-dan Zhu, Yun-zhi Wang, Chen Zou, Xin-ping She, more

Biochemical and Biophysical Research Communications > 2018 > 503 > 2 > 921-929

Uric acid has been proposed as an independent risk factor of diabetic retinopathy. Although Notch signaling was reported to be affected in the presence of high concentrations of uric acid or glucose, the underlying mechanisms of hyperuricemia through the Notch signaling pathway to promote the development of diabetic retinopathy remain unknown.We incubated human retinal endothelial cells (HRECs) with...

article

Characterization of the complete chloroplast genome of an endemic species of pea family in China, Ormosia hosiei (Fabaceae)

Jian-Qiang Zhang, Meng-Ying Jiang, Dan-Dan Zhu, Jia-Ling Zhang, more

Conservation Genetics Resources > 2019 > 11 > 4 > 443-446

Ormosia hosiei (Fagaceae), a critically endangered plant species, is famous for its excellent wood from which the carving craft and high-grade furniture can be made. In this study, we characterized the complete chloroplast genome of O. hosiei based on next generation sequencing to analyze its phylogenetic position. The circular complete chloroplast genome of O. hosiei was 171,642 bp in length, containing...

article

Reduction-sensitive micelles with detachable poly (2-ethyl-2-oxazoline) corona for enhanced intracellular doxorubicin delivery

Yu-Ling Li, Dan-Dan Zhu, Ting Xu, Bai-Xiang Du

Journal of Controlled Release > 2017 > 259 > C > e184

article

Structural optimization of rapidly separating microneedles for efficient drug delivery

Dan Dan Zhu, Bo Zhi Chen, Meng Chan He, Xin Dong Guo

Journal of Industrial and Engineering Chemistry > 2017 > 51 > C > 178-184

Rapidly separating microneedles (RSMNs) arose as an improvement of traditional MNs for the special separable structures. The aim of this study was to investigate various structural parameters contributed to the delivery performance of RSMNs. The experimental results indicated that the optimized RSMNs with 500μm-long solid PLA MNs, 250μm-long overlap and 500μm-long dissolving MNs delivered over 95%...

chapter

A new false root identification method based on two terminal fault location algorithm for high voltage transmission line

Shou-Peng Wang, Dong-Mei Zhao, Li-Qun Shang, Dan-Dan Zhu

2016 IEEE International Conference on Power and Renewable Energy (ICPRE) > 10 - 14

2016 IEEE International Conference on Power and Renewable Energy (ICPRE)

High voltage transmission line fault location algorithm without synchronization, which does not require sampling synchronization, reduces cost and has a higher practical engineering value. But the algorithm still needs to be improved in the false root identification of ranging equation, this paper makes a further research on this issue. Firstly, the false root problem of fault location algorithm without...

article

Rapidly separating microneedles for transdermal drug delivery

Dan Dan Zhu, Qi Lei Wang, Xu Bo Liu, Xin Dong Guo

Acta Biomaterialia > 2016 > 41 > C > 312-319

The applications of polymer microneedles (MNs) into human skin emerged as an alternative of the conventional hypodermic needles. However, dissolving MNs require many minutes to be dissolved in the skin and typically have difficulty being fully inserted into the skin, which may lead to the low drug delivery efficiency. To address these issues, we introduce rapidly separating MNs that can rapidly deliver...

article

A fabrication method of microneedle molds with controlled microstructures

Qi Lei Wang, Dan Dan Zhu, Yang Chen, Xin Dong Guo

Materials Science and Engineering: C > 2016 > 65 > C > 135-142

Microneedle (MN) offers an attractive, painless and minimally invasive approach for transdermal drug delivery. Polymer microneedles are normally fabricated by using the micromolding method employing a MN mold, which is suitable for mass production due to high production efficiency and repeat-using of the mold. Most of the MN molds are prepared by pouring sylgard polymer over a MN master to make an...

article

Significance of NF‐κB activation in immortalization of nasopharyngeal epithelial cells

Dan Dan Zhu, Jun Zhang, Wen Deng, Yim Ling Yip, more

International Journal of Cancer > 138 > 5 > 1175 - 1185

NF‐κB is a key regulator of inflammatory response and is frequently activated in human cancer including the undifferentiated nasopharyngeal carcinoma (NPC), which is common in Southern China including Hong Kong. Activation of NF‐κB is common in NPC and may contribute to NPC development. The role of NF‐κB activation in immortalization of nasopharyngeal epithelial (NPE) cells, which may represent an...

article

Mesoscopic simulation studies on the formation mechanism of drug loaded polymeric micelles

Yan Wang, Dan Dan Zhu, Jian Zhou, Qi Lei Wang, more

Colloids and Surfaces B: Biointerfaces > 2015 > 136 > C > 536-544

In this work, the formation of polymeric micelles as drug delivery vehicles in an aqueous environment is investigated by dissipative particle dynamics (DPD) simulations. Doxorubicin (DOX) is selected as the model drug, whereas docosahexaenoic acid (DHA) conjugated His10Lys10 (DHA-His₁₀Lys₁₀) as the drug carrier. It is shown from DPD simulation that drug molecules and DHA-His₁₀Lys₁₀ molecules could...

article

Three-component solvent-free synthesis of fluorine substituted bicyclic pyridines

Dan-Dan Zhu, Xue-Bing Chen, Rong Huang, Sheng-Jiao Yan, more

Tetrahedron > 2015 > 71 > 16 > 2363-2368

A concise and efficient one-pot three-component synthesis of structurally diverse fluorine substituted bicyclic pyridines was constructed by simply refluxing a mixture of different types of heterocyclic ketene aminals, triethoxymethane, and fluorine-containing methylene compounds under solvent-free and catalyst-free conditions. These bicyclic pyridines are promising candidates for drug discovery;...

article

Hierarchical porous activated carbon produced from spinach leaves as an electrode material for a electric double layer capacitor

Yu-jing Ou, Chao Peng, Jun-wei Lang, Dan-dan Zhu, more

Carbon > 2014 > 77 > C > 1196

Hierarchical porous activated carbon (AC) was obtained by the carbonization of dried spinach leaves followed by activation with KOH. The product was characterized by nitrogen adsorption, FT-IR, FE-SEM and electrochemical tests. The AC has a dominant number of micropores, a medium number of mesopores and a few macropores with a specific surface area up to 2616m²/g and a large number of oxygen-containing...

article

Hierarchical porous activated carbon produced from spinach leaves as an electrode material for an electric double layer capacitor

Yu-jing Ou, Chao Peng, Jun-wei Lang, Dan-dan Zhu, more

New Carbon Materials > 2014 > 29 > 3 > 209-215

Hierarchical porous activated carbon (AC) was obtained by the carbonization of dried spinach leaves followed by activation with KOH. The product was characterized by nitrogen adsorption, FT-IR, FE-SEM and electrochemical tests. The AC has a dominant number of micropores, a medium number of mesopores and a few macropores with a specific surface area up to 2616 m ² /g and a large number of oxygen-containing...

article

Three-component domino reaction synthesis of highly functionalized bicyclic pyrrole derivatives

Xue-Bing Chen, Xiao-Ying Wang, Dan-Dan Zhu, Sheng-Jiao Yan, more

Tetrahedron > 2014 > 70 > 5 > 1047-1054

An efficient one-pot synthesis of highly functionalized bicyclic pyrrole derivatives by a three-component domino reaction of heterocyclic ketene aminals (HKAs), arylglyoxal monohydrate, and indoles in ethanol medium catalyzed by acetic acid is described. In this procedure, three sigma bonds were formed simultaneously. The present synthesis features excellent regio-selectivity, easy purification as...

article

Modelling and applications of annual energy-using simulation module of separated heat pipe heat exchanger

Dan-dan Zhu, Da Yan, Zhen Li

Energy & Buildings > 2013 > 57 > Complete > 26-33

Separate heat pipe heat exchanger (SHP heat exchanger) transports heat from the indoor air to the outdoor air by making use of the temperature difference. It consumes much less energy than split air-conditioners in telecommunication base stations (TBSs) because of no compressor. In this paper an annual energy-using simulation module of SHP was built up in the building energy simulation tool DeST....

article

Protective effect of DNA vaccine with the gene encoding 55kDa antigen fragment against Pneumocystis carinii in mice

Yi-nong Duan, Liang-heng Yi, Jin-ling Chen, Dan-dan Zhu, more

Asian Pacific Journal of Tropical Medicine > 2011 > 4 > 5 > 353-356

To evaluate the protective effect of DNA vaccine with the gene encoding 55kDa antigen fragment of Pneumocystis carinii (P. carinii) against P. carinii in mice. The fragment of the antigen within p55(p55-582) was cloned. Then recombinant plasmid was constructed based on the eukaryotic expression vector pcDNA3.1(+). BALB/c mice were used as experimental models to examine the immunogenicity of pcDNA3...

INFONA - science communication portal

Search results for: Dan-dan Zhu

The main driving factors and responses to increase in soil available potassium in the Yangtze River basin over the past 30 years

The maximum possible amount of drug in rapidly separating microneedles

Macromol. Rapid Commun. 20/2018

Controlled Delivery of Insulin Using Rapidly Separating Microneedles Fabricated from Genipin‐Crosslinked Gelatin

Efficient adsorption separation of xylene isomers using a facilely fabricated cyclodextrin‐based metal–organic framework

The role of uric acid in the pathogenesis of diabetic retinopathy based on Notch pathway

Characterization of the complete chloroplast genome of an endemic species of pea family in China, Ormosia hosiei (Fabaceae)

Reduction-sensitive micelles with detachable poly (2-ethyl-2-oxazoline) corona for enhanced intracellular doxorubicin delivery

Structural optimization of rapidly separating microneedles for efficient drug delivery

A new false root identification method based on two terminal fault location algorithm for high voltage transmission line

Rapidly separating microneedles for transdermal drug delivery

A fabrication method of microneedle molds with controlled microstructures

Significance of NF‐κB activation in immortalization of nasopharyngeal epithelial cells

Mesoscopic simulation studies on the formation mechanism of drug loaded polymeric micelles

Three-component solvent-free synthesis of fluorine substituted bicyclic pyridines

Hierarchical porous activated carbon produced from spinach leaves as an electrode material for a electric double layer capacitor

Hierarchical porous activated carbon produced from spinach leaves as an electrode material for an electric double layer capacitor

Three-component domino reaction synthesis of highly functionalized bicyclic pyrrole derivatives

Modelling and applications of annual energy-using simulation module of separated heat pipe heat exchanger

Protective effect of DNA vaccine with the gene encoding 55kDa antigen fragment against Pneumocystis carinii in mice

Filter options

Publication date

Publication type

Keywords

Data set

Journal

INFONA - science communication portal

Search results for: Dan-dan Zhu

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Publication type

Keywords

Data set

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options