Asian Pacific Journal of Tropical Medicine

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Adjuncts to case assessment of vaginal discharge syndrome in pregnant women

JE Ekabua, TU Agan, CU Eklaki, EI Ekanew

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 63-65

To investigate the aetiology of abnormal vaginal discharge, using a non-culture based method, among pregnant women presenting at the University of Calabar Teaching Hospital, Calabar, Nigeria. Two hundred consecutive antenatal patients, aged 18 to 38 years, with complaints of abnormal vaginal discharge between 1st April and 31st July 2004 were investigated clinically for the characteristics of the...

article

Relapse typhoid fever in North–eastern state in Malaysia

Zakuan Zainy Deris, Siti Suraiya Md Noor, Nor Hashimah Abdullah, Abdul Rahman Noor

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 48-50

To discuss the prevalence, clinical and laboratory presentations of relapse typhoid fever. All relapse cases were reviewed to identify the clinical and laboratory presentation of the relapse typhoid fever. Two hundred and forty six patients were admitted to a teaching tertiary hospital in North-eastern state of Malaysia and fourteen (5.69%) relapse cases were identified. The duration of relapse...

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Pattern and antibiogram of urinary tract infection at the University of Port Harcourt Teaching Hospital

KT Wariso, IM Siminialayi, JO Odigie

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 66-69

To explore the prevalence, pathogenicity, and antibiotic susceptibility patterns of urinary tract infections at the University of Port Harcourt Teaching Hospital. Samples from 400 patients with a presumptive diagnosis of urinary tract infection including 250 non pregnant females and 150 males were used for this study. They were distributed into two groups: children aged 2 to 17 (Group A) and adults...

article

The importance of different forms of prevention in travel medicine

Peter Felkai

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 74-77

The Asia–Pacific region is becoming an increasingly popular destination for holidaymakers and business travelers. Despite the seductive tourist attractions and the growing financial importance of the region, infectious diseases have unfortunately repeatedly caused major epidemics in the region. The area includes various geographical situations from high mountains to the subtropical and monsoon forests,...

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Immunomodulating property of Ocimum sanctum by regulating the IL-2 production and its mRNA expression using rat's splenocytes

Anjana Goel, Dilip Kumar Singh, Sandeep Kumar, Ashok Kumar Bhatia

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 8-12

To investigate the regulatory effect of aqueous extract of leaves of Ocimum sanctum on IL-2 cytokine production in vivo and in vitro, and the effect of leaves extract on general blood picture including T& B lymphocytes. For in vivo studies albino Wistar rats were treated with aqueous crude leaves extract of Ocimum sanctum for 20 consecutive days. Spleen cells were harvested and assayed for...

article

A study on utilization of anti–asthmatic drugs at a medical college hospital in India

Shalini Ravichandran, Vipin Mathew, Vijesh, Shaheer, more

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 70-73

To study the usage of anti-asthmatic dugs and enumerate the patients' non-compliance. The study was conducted from 5th Feb, 2006 to 5th Mar, 2006. The samples were from the general medicine ward. All patients with respiratory tract infection who received anti–asthmatic drugs were included in the study. Data were collected from clinical notes and structured patient's data, and patient interview...

article

Staphylococcus aureus β-hemolysin-neutralizing single-domain antibody isolated from phage display library of Indian desert camel

Pooja Jangra, Ajit Singh

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 1-7

To isolate and characterize Staphylococcus aureus (S. aureus) β-hemolysin-neutralizing dAbs from phage display library of Indian desert camel. Phage display library of 5×10 ⁷ dAb clones of LPS-immunized Indian desert camel constructed in our laboratory was used for selection of S. aureus exotoxin-specific clones by panning technique. Enrichment of Ag-specific clones in successive rounds...

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Detection of virulent strains of Helicobacter pylori and its relation to symptoms and signs in children

S Fayed, S Abd El Dayem, H Hussein, M Sherief, more

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 59-62

To detect the prevalence of Helicobacter polori (H. pylori) in a group of pediatric patients complaining of gastrointestinal disorders, and to identify the virulent strains of H. pylori and its relation to peptic disease. The study included 60 patients (41 males and 19 females), aged from 6 months to 14 years, with complaining of different gastrointestinal troubles. Anti-H. pylori IgG antibodies...

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Evaluation of the anticonvulsant and muscle relaxant effects of the methanol root bark extracts of Annona senegalensis

TC Okoye, PA Akah, CP Omeke

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 25-28

To investigate the potentials of the root bark of Annona (A.) senegalensis in the control of seizure and related hypnotic and motor incoordination effects in mice using experimental models. The methanol extract (ME) of the root bark of A. senegalensis was studied in mice using pentylenetetrazole (PTZ) induced convulsions, phenobarbitone induced sleeping time and motor coordination test on rota-rod...

article

Survey of epidemiology and bacteriology features of cholera in Iran

Mohammad Rahbar, Mohsen Zahraei, Aboulgasm Omidvarnia, Mohammad Taqi Afshani, more

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 45-47

To determine epidemiology and antimicrobial susceptibility patterns of Vibrio (V.) cholerae O1 biotype EL Tor in summer outbreak of 2008 in Iran. Stool samples were collected from patients suspected to have cholera admitted to hospitals and clinics. Specimens examined by conventional bacteriological methods. All isolates were sent to cholera reference laboratory for further confirmation, stereotyping...

article

Evaluation of the antiulcer activity of Olax subscorpioidea Oliv. roots in rats

Ukwe Chinwe Victoria, Ubaka Chukwuemeka Michael, Madusque Uche Johnny

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 13-16

To evaluate the antiulcer activity of the methanolic root extract of the plant Olax subscorpioidea in experimental rats. Phytochemical tests and acute toxicity tests were carried out on its methanolic root extract. Pre-treatments with three doses of the extract (200, 400 and 600 mg/kg body weight orally) and Sucralfate at 100 mg/kg orally were used for the various groups of rats. The indomethacin...

article

Transitional metal ions induced damage to biomolecules: role of ferryl and perferryl radicals

Mungli Prakash, Sharmila Upadhya

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 32-35

To investigate the effect of oxidized transitional metal (ferric and cupric) ions on the amino acids. 25 mmol/L hydroxyproline and 25 mmol/L histidine were incubated with 50 μL Fe ³⁺ and Cu ²⁺ ions at pH 7.4 and 37 °C for 30 mins in separate test tubes. Then 500 μL of 1% thiobarbituricacid (TBA) was added to the incubated amino acids followed by addition of 500 μL of glacial acetic...

article

Pro–and anti–inflammatory cytokines profiles among Nigerian children infected with Plasmodium falciparum malaria

OPG Nmorsi, C Isaac, NCD Ukwandu, BA Ohaneme

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 41-44

To examine array of some pro-and anti-inflammatory cytokines, namely, interleukin-4 (IL-4), interleukin-10 (IL-10), interferon-γ (IFN-γ), interleukin-5(IL-5), interleukin-6 (IL-6), interleukin-12 (IL-12) and tumor necrosis factor-α (TNF-α) concentrations in some Nigerians with falciparum malaria. Sera were obtained from the blood samples of 96 Nigerian children with Plasmodium falciparum infection...

article

Prevalence of asymptomatic malaria parasitaemia

TU Agan, JE Ekabua, CU Iklaki, A Oyo–Ita, more

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 51-54

To evaluate factors associated with prevalence of malaria parasitaemia at first antenatal care visit. The study was conducted at the University of Calabar Teaching Hospital from 1st June, 2007 to 31st July, 2007. A structured questionnaire was administered to a total of 545 pregnant women that were recruited in this study after obtaining informed consent and two slides of thin and thick films were...

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The effects of aqueous extracts of Tetracarpidium conophorum seeds on the hormonal parameters of male guinea pigs

AW Obianime, FI Uche

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 21-24

To investigate the effects of the aqueous extracts of the seeds of Tetracarpidium conophorum and the effect of Proviron (12.5 mg/kg) (as standard) on the hormonal parameters of male guinea pigs, compare the effects of the seeds of Tetracarpidium conophorumand Proviron, and screen the phytochemical constituents of the seeds of Tetracarpidium conophorum. The hormonal effects of the Tetracarpidium...

article

A qualitative study on the adverse reactions of mass treatment for lymphatic filariasis in Orissa, India

BV Babu

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 55-58

To describe the perceptions of community members and programme partners regarding severity, management and impact of adverse reactions on mass drug administration (MDA) compliance. Based on various qualitative data collected from five districts of Orissa, India, where MDA had been implemented during 2002 and 2004. The qualitative surveys included focus group discussions with community members and...

article

The extract of Mucuna pruriens possesses histamine activity

Reginald NP Nwankwoala, OA Georgewill

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 29-31

To investigate the activity of the active principle in the spines of the seed pods of Mucuna pruriens using contraction of guinea pig ileum as index of pharmacological activity. The active principle was extracted with 0.0015 M NaCl. Muscle strips of guinea pig ileum were prepared and contractile responses were measured using a Kymograph. Two sets of experiment were conducted: (1). The contraction...

article

Swine flu pandemic: a global concern

Asad U Khan

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 81-82

Recently WHO has again declared Influenza pandemic due to the outbreak of H1N1 which has infected over 254,206 people in 80 countries, with 625 deaths. Our lab has started working on the proteome analysis of H1N1, 2009 out break strains.

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A successful TB defaulter control in a war zone with high HIV prevalence

Giovanni Landoni, Chiara Pierotti, Barbara Nattabi, Joyce Nono, more

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 78-80

War zones in Sub-Saharan Africa represent a challenge for public health projects like TB control programs because planning and communication have been disrupted, doctors and medical workers flied to secure zones. We present a TB control program carried out by an Italian NGO, Italian Association for Solidarity among People (AISPO) in a referral Hospital of North Uganda (Lacor H).

article

Hepatoprotective effect of Premna corymbosa (Burm. f.) Rottl. & Willd. leaves extract on CCl4 induced hepatic damage in Wistar albino rats

M Karthikeyan, K Deepa

Asian Pacific Journal of Tropical Medicine > 2010 > 3 > 1 > 17-20

To investigate the hepetoprotective activity of Premna corymbosa leaves against carbon tetrachloride (CCl ₄ ) induced hepatic damage. Hepatotoxicity was induced in wistar rats of both sexes by intraperitoneal injection of CCl ₄ , 1 mL/kg body weight for every 72 h. The ethanolic extract of Premna corymbosa leaves were administrated at doses of 200 & 400 mL/kg body weight, p...

INFONA - science communication portal

Asian Pacific Journal of Tropical Medicine

Adjuncts to case assessment of vaginal discharge syndrome in pregnant women

Relapse typhoid fever in North–eastern state in Malaysia

Pattern and antibiogram of urinary tract infection at the University of Port Harcourt Teaching Hospital

The importance of different forms of prevention in travel medicine

Immunomodulating property of Ocimum sanctum by regulating the IL-2 production and its mRNA expression using rat's splenocytes

A study on utilization of anti–asthmatic drugs at a medical college hospital in India

Staphylococcus aureus β-hemolysin-neutralizing single-domain antibody isolated from phage display library of Indian desert camel

Detection of virulent strains of Helicobacter pylori and its relation to symptoms and signs in children

Evaluation of the anticonvulsant and muscle relaxant effects of the methanol root bark extracts of Annona senegalensis

Survey of epidemiology and bacteriology features of cholera in Iran

Evaluation of the antiulcer activity of Olax subscorpioidea Oliv. roots in rats

Transitional metal ions induced damage to biomolecules: role of ferryl and perferryl radicals

Pro–and anti–inflammatory cytokines profiles among Nigerian children infected with Plasmodium falciparum malaria

Prevalence of asymptomatic malaria parasitaemia

The effects of aqueous extracts of Tetracarpidium conophorum seeds on the hormonal parameters of male guinea pigs

A qualitative study on the adverse reactions of mass treatment for lymphatic filariasis in Orissa, India

The extract of Mucuna pruriens possesses histamine activity

Swine flu pandemic: a global concern

A successful TB defaulter control in a war zone with high HIV prevalence

Hepatoprotective effect of Premna corymbosa (Burm. f.) Rottl. & Willd. leaves extract on CCl4 induced hepatic damage in Wistar albino rats

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