Search results for: Edward J. Golob

Items from 1 to 20 out of 21 results

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Auditory spatial attention gradients and cognitive control as a function of vigilance

Edward J. Golob, Jeremy T. Nelson, Jaelle Scheuerman, Kristen B. Venable, more

Selection and effort are central to attention, yet it is unclear whether they draw on a common pool of cognitive resources, and if so, whether there are differences for early versus later stages of cognitive processing. This study assessed effort by quantifying the vigilance decrement, and spatial processing at early and later stages as a function of time‐on‐task. Participants performed an auditory...

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Strategic encoding and retrieval processes in verbal recall among middle‐aged and older adults

Katie E. Cherry, Emily M. Elliott, Edward J. Golob, Jennifer Silva Brown, more

British Journal of Developmental Psychology > 39 > 2 > 252 - 268

The authors used an analysis of individual differences to examine the role of executive control in strategic encoding and retrieval in verbal recall. Participants enrolled in the Louisiana Healthy Aging Study completed measures of working memory (WM), cognitive status, vocabulary, and free recall of words. Indices of clustering in free recall were calculated to permit inferences on strategic encoding...

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Auditory spatial attention capture, disengagement, and response selection in normal aging

Edward J. Golob, Jeffrey R. Mock

Attention, Perception, & Psychophysics > 2019 > 81 > 1 > 270-280

Attention control is a core element of cognitive aging, but the specific mechanisms that differ with age are unclear. Here we used a novel auditory spatial attention task to evaluate stimulus processing at the level of early attention capture, later response selection, and the lingering effects of attention capture across trials in young and older adults. We found that the shapes of spatial attention...

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Cortical activity during cued picture naming predicts individual differences in stuttering frequency

Jeffrey R. Mock, Anne L. Foundas, Edward J. Golob

Clinical Neurophysiology > 2016 > 127 > 9 > 3093-3101

Developmental stuttering is characterized by fluent speech punctuated by stuttering events, the frequency of which varies among individuals and contexts. Most stuttering events occur at the beginning of an utterance, suggesting neural dynamics associated with stuttering may be evident during speech preparation.This study used EEG to measure cortical activity during speech preparation in men who stutter,...

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Focused and divided attention in a simulated cocktail-party situation: ERP evidence from younger and older adults

Stephan Getzmann, Edward J. Golob, Edmund Wascher

Neurobiology of Aging > 2016 > 41 > C > 138-149

Speech perception under complex listening conditions usually decreases in aging. This is especially true for listening conditions requiring divided attention among 2 and more relevant speakers. Using a speech perception task and event-related potential measures, we studied the ability of younger and older adults to attend to speech information from a single-target speaker (focused attention) or from...

article

Speech preparation in adults with persistent developmental stuttering

Jeffrey R. Mock, Anne L. Foundas, Edward J. Golob

Brain and Language > 2015 > 149 > Complete > 97-105

Motor efference copy conveys movement information to sensory areas before and during vocalization. We hypothesized speech preparation would modulate auditory processing, via motor efference copy, differently in men who stutter (MWS) vs. fluent adults. Participants (n=12/group) had EEG recorded during a cue-target paradigm with two conditions: speech which allowed for speech preparation, while a control...

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Enhancing vigilance in operators with prefrontal cortex transcranial direct current stimulation (tDCS)

Jeremy T. Nelson, R. Andy McKinley, Edward J. Golob, Joel S. Warm, more

NeuroImage > 2014 > 85 > Part 3 > 909-917

Sustained attention, often referred to as vigilance in humans, is the ability to maintain goal-directed behavior for extended periods of time and respond to intermittent targets in the environment. With greater time-on-task the ability to detect targets decreases and reaction time increases—a phenomenon termed the vigilance decrement. The purpose of this study was to examine the role of dorsolateral...

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Cortical potentials in an auditory oddball task reflect individual differences in working memory capacity

Kate A. Yurgil, Edward J. Golob

Psychophysiology > 50 > 12 > 1263 - 1274

This study determined whether auditory cortical responses associated with mechanisms of attention vary with individual differences in working memory capacity (WMC) and perceptual load. The operation span test defined subjects with low versus high WMC, who then discriminated target/nontarget tones while EEG was recorded. Infrequent white noise distracters were presented at midline or ±90° locations,...

article

The SpeechEasy device in stuttering and nonstuttering adults: Fluency effects while speaking and reading

Anne L. Foundas, Jeffrey R. Mock, David M. Corey, Edward J. Golob, more

Brain and Language > 2013 > 126 > 2 > 141-150

The SpeechEasy is an electronic device designed to alleviate stuttering by manipulating auditory feedback via time delays and frequency shifts. Device settings (control, default, custom), ear-placement (left, right), speaking task, and cognitive variables were examined in people who stutter (PWS) (n=14) compared to controls (n=10). Among the PWS there was a significantly greater reduction in stuttering...

article

Cortical mechanisms of auditory spatial attention in a target detection task

Edward J. Golob, John L. Holmes

Brain Research > 2011 > 1384 > Complete > 128-139

The benefits of spatial attention on stimulus processing are thought to diminish with increased distance from the attended location, indicating an attention gradient. Evidence for attention gradients is provided by spatial attention effects on event-related potentials (ERPs) under conditions of rapid stimulus presentation from closely spaced locations. This study was motivated by ecological considerations...

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Modulation of sensory and motor cortex activity during speech preparation

Jeffrey R. Mock, Anne L. Foundas, Edward J. Golob

European Journal of Neuroscience > 33 > 5 > 1001 - 1011

Previous studies have shown that speaking affects auditory and motor cortex responsiveness, which may reflect the influence of motor efference copy. If motor efference copy is involved, it would also likely influence auditory and motor cortical activity when preparing to speak. We tested this hypothesis by using auditory event‐related potentials and transcranial magnetic stimulation (TMS) of the motor...

article

ApoE genotype and abnormal auditory cortical potentials in healthy older females

Rie Irimajiri, Edward J. Golob, Arnold Starr

Neurobiology of Aging > 2010 > 31 > 10 > 1799-1804

Apolipoprotein E (ApoE) status and gender are risk factors for the development of Alzheimer's disease. Alzheimer's disease is more prevalent in female relative to male carriers of the ApoE ɛ4 gene. We examined cortical sensory (P50, N100) and cognitive (P300) potentials in an auditory target detection task in females as a function of ApoE genotype (ApoE ɛ4 carriers, ApoE ɛ4 non-carriers) to define...

article

Neural activity before and after conscious perception in dichotic listening

Kate A. Yurgil, Edward J. Golob

Neuropsychologia > 2010 > 48 > 10 > 2952-2958

The neural basis of conscious perception can be studied using stimuli that elicit different percepts on different occasions (multistable perception). Multistable perception allows direct comparisons between brain activity and conscious perception that control for sensory input, and also serves as a model for attentional competition, with the winning perceptual outcome varying across trials. Dichotic...

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Cholinesterase inhibitors affect brain potentials in amnestic mild cognitive impairment

Rie Irimajiri, Henry J. Michalewski, Edward J. Golob, Arnold Starr

Brain Research > 2007 > 1145 > Complete > 108-116

Amnestic mild cognitive impairment (MCI) is an isolated episodic memory disorder that has a high likelihood of progressing to Alzheimer's disease. Auditory sensory cortical responses (P50, N100) have been shown to be increased in amplitude in MCI compared to older controls. We tested whether (1) cortical potentials to other sensory modalities (somatosensory and visual) were also affected in MCI and...

article

Event-related potentials accompanying motor preparation and stimulus expectancy in the young, young-old and oldest-old

Edward J. Golob, Vahagn Ovasapyan, Arnold Starr

Neurobiology of Aging > 2005 > 26 > 4 > 531-542

Although aging is accompanied by neurobiological changes and increased susceptibility to many neurological disorders, little is known about neurophysiological changes that start in old age. Here, neurophysiological changes during old age were assessed by recording brain potentials associated with motor preparation and stimulus expectancy (contingent negative variation, CNV) in young-old (60-69), oldest-old...

article

Age-related differences in auditory event-related potentials during a cued attention task

Ilana J. Bennett, Edward J. Golob, Arnold Starr

Clinical Neurophysiology > 2004 > 115 > 11 > 2602-2615

Objective: To determine if aging is associated with differences in attentional regulation using behavioral and event-related potential (ERP) measures.Methods: Younger (n=13;M=20 years) and older (n=12;M=76 years) subjects performed an auditory cued attention task. Verbal cues correctly (valid) or incorrectly (invalid) predicted the ear receiving a target tone 1.5 s later, or were uninformative (neutral)...

article

Differences between appetitive and aversive reinforcement on reorientation in a spatial working memory task

Edward J. Golob, Jeffrey S. Taube

Behavioural Brain Research > 2002 > 136 > 1 > 309 - 316

Tasks using appetitive reinforcers show that following disorientation rats use the shape of an arena to reorient, and cannot distinguish two geometrically similar corners to obtain a reward, despite the presence of a prominent visual cue that provides information to differentiate the two corners. Other studies show that disorientation impairs performance on certain appetitive, but not aversive, tasks...

article

Auditory event-related potentials during target detection are abnormal in mild cognitive impairment

Edward J Golob, J.K Johnson, A Starr

Clinical Neurophysiology > 2002 > 113 > 1 > 151-161

Objective: To define brain activity and behavioral changes in mild cognitive impairment (MCI), an isolated memory deficit in the elderly that is a major risk factor for Alzheimer's disease.Methods: Brain potentials and reaction time were examined in elderly controls (n=12) and MCI (n=15) using a target detection paradigm. Subjects listened to a sequence of tones and responded to high-pitched target...

article

Sensory cortical interactions in aging, mild cognitive impairment, and Alzheimer’s disease

Edward J. Golob, Gemma G. Miranda, Julene K. Johnson, Arnold Starr

Neurobiology of Aging > 2001 > 22 > 5 > 755-763

Progressive declines in memory function accompany normal aging, mild cognitive impairment (MCI), and Alzheimer’s disease (AD). Neuropathological studies suggest that damage to neurons providing connections between cortical areas may contribute to memory impairments in AD. Because AD develops slowly, similar neuropathological changes, to a lesser degree, may be present in MCI and some asymptomatic...

article

Event-related potentials and reaction time can distinguish healthy aging from mild Alzheimer's disease

Edward J. Golob, Arnold Starr

Neurobiology of Aging > 2000 > 21 > Supplement 1 > 229

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Search results for: Edward J. Golob

Auditory spatial attention gradients and cognitive control as a function of vigilance

Strategic encoding and retrieval processes in verbal recall among middle‐aged and older adults

Auditory spatial attention capture, disengagement, and response selection in normal aging

Cortical activity during cued picture naming predicts individual differences in stuttering frequency

Focused and divided attention in a simulated cocktail-party situation: ERP evidence from younger and older adults

Speech preparation in adults with persistent developmental stuttering

Enhancing vigilance in operators with prefrontal cortex transcranial direct current stimulation (tDCS)

Cortical potentials in an auditory oddball task reflect individual differences in working memory capacity

The SpeechEasy device in stuttering and nonstuttering adults: Fluency effects while speaking and reading

Cortical mechanisms of auditory spatial attention in a target detection task

Modulation of sensory and motor cortex activity during speech preparation

ApoE genotype and abnormal auditory cortical potentials in healthy older females

Neural activity before and after conscious perception in dichotic listening

Cholinesterase inhibitors affect brain potentials in amnestic mild cognitive impairment

Event-related potentials accompanying motor preparation and stimulus expectancy in the young, young-old and oldest-old

Age-related differences in auditory event-related potentials during a cued attention task

Differences between appetitive and aversive reinforcement on reorientation in a spatial working memory task

Auditory event-related potentials during target detection are abnormal in mild cognitive impairment

Sensory cortical interactions in aging, mild cognitive impairment, and Alzheimer’s disease

Event-related potentials and reaction time can distinguish healthy aging from mild Alzheimer's disease

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