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Osteoclasts (OC) are key players in bone destruction in rheumatoid arthritis (RA). Recent work showed that catecholaminergic nerve fibers are reduced in RA synovial tissue. Studies on sweat gland innervation revealed that catecholaminergic fibers are capable of phenotypic transition to cholinergic nerves. The sympathetic neurotransmitters norepinephrine (NE) and acetylcholine (ACh) affect osteoclastogenesis...
Meristems of seed plants continuously produce new cells for incorporation into maturing tissues. A tightly controlled balance between cell proliferation in the center and cell differentiation at the periphery of the shoot meristem maintains its integrity. Here, we describe the role of three GRAS genes, named LOST MERISTEMS genes, in shoot apical meristem maintenance and axillary meristem formation...
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