Search results for: Han Bao

Items from 1 to 20 out of 72 results

article

Formate‐tetrahydrofolate ligase: supplying the cytosolic one‐carbon network in roots with one‐carbon units originating from glycolate

Sompop Saeheng, Clayton Bailes, Han Bao, Kelem Gashu, more

The Plant Journal > 119 > 5 > 2464 - 2483

The metabolism of tetrahydrofolate (H₄PteGlu_n)‐bound one‐carbon (C₁) units (C₁ metabolism) is multifaceted and required for plant growth, but it is unclear what of many possible synthesis pathways provide C₁ units in specific organelles and tissues. One possible source of C₁ units is via formate‐tetrahydrofolate ligase, which catalyzes the reversible ATP‐driven production of 10‐formyltetrahydrofolate...

article

Untargeted metabolomics revealed the effect of soybean metabolites on poly(γ‐glutamic acid) production in fermented natto and its metabolic pathway

Delin Yan, Lei Huang, Zhiqing Mei, Han Bao, more

Journal of the Science of Food and Agriculture > 104 > 3 > 1298 - 1307

BACKGROUND Natto mucus is mainly composed of poly(γ‐glutamic acid) (γ‐PGA), which affects the sensory quality of natto and has some effective functional activities. The soybean metabolites that cause different γ‐PGA contents in different fermented natto are unclear. RESULTS In this study, we use untargeted metabolomics to analyze the metabolites of high‐production γ‐PGA natto and low‐production...

article

Emerging Nanoporous Materials for Biomolecule Separation

Yongyang Song, Han Bao, Xinyi Shen, Xiuling Li, more

Advanced Functional Materials > 32 > 20 > n/a - n/a

Biomolecule separation plays a vital role in downstream applications ranging from omics research, structure analysis, and drug purification to clinical diagnosis. Among all existing materials and technologies towards biomolecule separation, nanoporous materials take the leading place. To achieve efficient biomolecule separation, the interface of nanoporous materials is always modified with a monolayer...

article

Thermo‐Responsive Jamming of Nanoparticle Dense Suspensions towards Macroscopic Liquid–Solid Switchable Materials

Mingqian Liu, Xizi Wan, Man Yang, Zhao Wang, more

Angewandte Chemie > 134 > 4 > n/a - n/a

Nanoparticle aggregation for constructing functional materials has shown enormous advantages in various applications. Most efforts focused on ordered nanoparticle aggregation for specific functions but were often limited to irreversible aggregation processes due to the thermodynamic equilibrium. Herein, we report a reversible disordered aggregation of SiO₂‐PNIPAAm nanoparticles (SPNPs) through thermo‐responsive...

article

Thermo‐Responsive Jamming of Nanoparticle Dense Suspensions towards Macroscopic Liquid–Solid Switchable Materials

Mingqian Liu, Xizi Wan, Man Yang, Zhao Wang, more

Angewandte Chemie International Edition > 61 > 4 > n/a - n/a

article

Evaporation‐Induced rGO Coatings for Highly Sensitive and Non‐Invasive Diagnosis of Prostate Cancer in the PSA Gray Zone

Binshuai Wang, Shudong Zhang, Jingxin Meng, Li Min, more

Advanced Materials > 33 > 40 > n/a - n/a

The prostate‐specific antigen (PSA) has been widely used for the early diagnosis of prostate cancer during routine check‐ups. However, the low sensitivity of regular PSA tests in the PSA gray zone often means that patients are required to undergo further invasive needle biopsy for the diagnosis of prostate cancer, which may lead to potential overdiagnosis and overtreatment. In this study, a circulating...

article

Platelet‐derived microvesicles promote endothelial progenitor cell proliferation in intimal injury by delivering TGF‐β1

Jing Yan, Han Bao, Yang‐Jing Fan, Zong‐Lai Jiang, more

The FEBS Journal > 287 > 23 > 5196 - 5217

Intimal injury is an early stage of several cardiovascular diseases. Endothelial progenitor cells (EPCs) play a significant role in endothelial repair following vascular injury. Once the intima is damaged, EPCs are mobilized from the bone marrow to the injury site. Meanwhile, the injury to the intimal surface triggers platelet degranulation, aggregation, and adhesion to the damaged endothelium, and...

article

Lamin A/C negatively regulated by miR‐124‐3p modulates apoptosis of vascular smooth muscle cells during cyclic stretch application in rats

Han Bao, Hai‐Peng Li, Qian Shi, Kai Huang, more

Acta Physiologica > 228 > 3 > n/a - n/a

Aim Apoptosis of vascular smooth muscle cells (VSMCs) influenced by abnormal cyclic stretch is crucial for vascular remodelling during hypertension. Lamin A/C, a nuclear envelope protein, is mechano‐responsive, but the role of lamin A/C in VSMC apoptosis is still unclear. Methods FX‐5000T Strain Unit provided cyclic stretch (CS) in vitro. AnnexinV/PI and cleaved Caspase 3 ELISA detected apoptosis...

article

Bursting oscillations and coexisting attractors in a simple memristor-capacitor-based chaotic circuit

Ning Wang, Guoshan Zhang, Han Bao

Nonlinear Dynamics > 2019 > 97 > 2 > 1477-1494

The design and analysis of a simple autonomous memristive chaotic circuit are important in theoretical, numerical, and experimental demonstrations of complex dynamics. In this paper, a simple autonomous memristive circuit is implemented, which only consists of an active second-order memristive diode bridge and a capacitor. Based on the available circuit, the mathematical model is established and its...

article

Canonical Correlation Analysis of Selecting Optimal Ground Motion Intensity Measures for Bridges

Shuai Song, Cong Qian, Yongjiu Qian, Han Bao, more

KSCE Journal of Civil Engineering > 2019 > 23 > 7 > 2958-2970

The correlation between ground motion intensity measures (IMs) and that between component seismic demand parameters (DPs) have significant effects on the seismic demand of bridges. A canonical correlation analysis method was introduced to consider the two types of correlations in the optimal selection of IMs for probabilistic seismic demand analysis of bridges. A group of 100 ground motion-bridge...

article

Hidden extreme multistability and dimensionality reduction analysis for an improved non-autonomous memristive FitzHugh–Nagumo circuit

Han Bao, Wenbo Liu, Mo Chen

Nonlinear Dynamics > 2019 > 96 > 3 > 1879-1894

Due to the introduction of ideal memristors, extreme multistability has been found in many autonomous memristive circuits. However, such extreme multistability has not yet been reported in a non-autonomous memristive circuit. To this end, this paper presents an improved non-autonomous memristive FitzHugh–Nagumo circuit that possesses a smooth hyperbolic tangent memductance nonlinearity, from which...

article

Characterization and comparative analysis of toxin–antitoxin systems in Acetobacter pasteurianus

Kai Xia, Han Bao, Fuming Zhang, Robert J. Linhardt, more

Journal of Industrial Microbiology & Biotechnology > 2019 > 46 > 6 > 869-882

Bacterial toxin–antitoxin (TA) systems play important roles in diverse cellular regulatory processes. Here, we characterize three putative type II TA candidates from Acetobacter pasteurianus and investigate the profile of type II TA systems in the genus Acetobacter. Based on the gene structure and activity detection, two-pairs loci were identified as the canonical hicAB and higAB TA systems, respectively,...

article

MicroRNA‐129‐1‐3p regulates cyclic stretch–induced endothelial progenitor cell differentiation by targeting Runx2

Na Li, Wen‐Bin Wang, Han Bao, Qian Shi, more

Journal of Cellular Biochemistry > 120 > 4 > 5256 - 5267

Endothelial progenitor cells (EPCs) are vital to the recovery of endothelial function and maintenance of vascular homeostasis. EPCs mobilize to sites of vessel injury and differentiate into mature endothelial cells (ECs). Locally mobilized EPCs are exposed to cyclic stretch caused by blood flow, which is important for EPC differentiation. MicroRNAs (miRNAs) have emerged as key regulators of several...

article

Regulation of Tip60‐dependent p53 acetylation in cell fate decision

Ping Wang, Han Bao, Xiao‐Peng Zhang, Feng Liu, more

FEBS Letters > 593 > 1 > 13 - 22

The acetylation of p53 plays an essential role in regulating its transcriptional activity. Nevertheless, how p53 acetylation is modulated in cell fate decision is less understood. We developed a network model to reveal how Tip60‐dependent p53 acetylation is regulated to modulate cellular outcome. We proposed that p53 is progressively activated and exhibits distinct dynamics depending on the severity...

article

Coexisting multi-stable patterns in memristor synapse-coupled Hopfield neural network with two neurons

Chengjie Chen, Jingqi Chen, Han Bao, Mo Chen, more

Nonlinear Dynamics > 2019 > 95 > 4 > 3385-3399

When possessing a potential difference between two neurons, an electromagnetic induction current appears in the Hopfield neural network (HNN), which can be emulated by a flux-controlled memristor synapse. Thus, a three-order two-neuron-based autonomous memristive HNN is presented in this paper, which is the lowest order and has not been reported in the previous studies. With the mathematical model,...

article

Inductor-free multi-stable Chua’s circuit constructed by improved PI-type memristor emulator and active Sallen–Key high-pass filter

Jiaoyan Luo, Han Bao, Mo Chen, Quan Xu, more

The European Physical Journal Special Topics > 2019 > 228 > 10 > 1983-1994

Based on an improved proportion-integral-type (PI-type) memristor emulator and an active Sallen–Key high-pass filter (HPF), a new memristive Chua’s circuit with inductor-free implementation is presented in this paper. The memristive Chua’s circuit possesses a line equilibrium state with unstable and stable region distributions, leading to the emergence of multi-stable patterns, i.e., the coexistence...

article

Coexisting multiple firing patterns in two adjacent neurons coupled by memristive electromagnetic induction

Han Bao, Wenbo Liu, Aihuang Hu

Nonlinear Dynamics > 2019 > 95 > 1 > 43-56

The membrane potential difference between two adjacent neurons can induce an electromagnetic induction current that behaves like a memristor synapse effect using to couple these two neurons. Based on two-dimensional (2D) Hindmarsh–Rose (HR) neuron and non-ideal threshold memristor, this paper presents a five-dimensional (5D) neuron model of two adjacent neurons coupled by memristive electromagnetic...

article

Convex formulation of multiple instance learning from positive and unlabeled bags

Han Bao, Tomoya Sakai, Issei Sato, Masashi Sugiyama

Neural Networks > 2018 > 105 > C > 132-141

Multiple instance learning (MIL) is a variation of traditional supervised learning problems where data (referred to as bags) are composed of sub-elements (referred to as instances) and only bag labels are available. MIL has a variety of applications such as content-based image retrieval, text categorization, and medical diagnosis. Most of the previous work for MIL assume that training bags are fully...

article

Double pincer movement: Encircling rupture splitting during the 2015 Mw 8.3 Illapel earthquake

Lingsen Meng, Han Bao, Hui Huang, Ailin Zhang, more

Earth and Planetary Science Letters > 2018 > 495 > C > 164-173

The 2015 moment magnitude (Mw) 8.3 Illapel earthquake, that ruptured the central section of the Chilean subduction zone, is among the largest megathrust events in recent years. The coseismic rupture processes of the Illapel earthquake are imaged by the back-projection (BP) method in previous studies. But these models differ significantly in the extent of high-frequency radiations in the along-dip...

article

Initial condition-dependent dynamics and transient period in memristor-based hypogenetic jerk system with four line equilibria

Han Bao, Ning Wang, Bocheng Bao, Mo Chen, more

Communications in Nonlinear Science and Numerical Simulation > 2018 > 57 > C > 264-275

Memristor-based nonlinear dynamical system easily presents the initial condition-dependent dynamical phenomenon of extreme multistability, i.e., coexisting infinitely many attractors, which has been received much attention in recent years. By introducing an ideal and active flux-controlled memristor into an existing hypogenetic chaotic jerk system, an interesting memristor-based chaotic system with...

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INFONA - science communication portal

Search results for: Han Bao

Formate‐tetrahydrofolate ligase: supplying the cytosolic one‐carbon network in roots with one‐carbon units originating from glycolate

Untargeted metabolomics revealed the effect of soybean metabolites on poly(γ‐glutamic acid) production in fermented natto and its metabolic pathway

Emerging Nanoporous Materials for Biomolecule Separation

Thermo‐Responsive Jamming of Nanoparticle Dense Suspensions towards Macroscopic Liquid–Solid Switchable Materials

Thermo‐Responsive Jamming of Nanoparticle Dense Suspensions towards Macroscopic Liquid–Solid Switchable Materials

Evaporation‐Induced rGO Coatings for Highly Sensitive and Non‐Invasive Diagnosis of Prostate Cancer in the PSA Gray Zone

Platelet‐derived microvesicles promote endothelial progenitor cell proliferation in intimal injury by delivering TGF‐β1

Lamin A/C negatively regulated by miR‐124‐3p modulates apoptosis of vascular smooth muscle cells during cyclic stretch application in rats

Bursting oscillations and coexisting attractors in a simple memristor-capacitor-based chaotic circuit

Canonical Correlation Analysis of Selecting Optimal Ground Motion Intensity Measures for Bridges

Hidden extreme multistability and dimensionality reduction analysis for an improved non-autonomous memristive FitzHugh–Nagumo circuit

Characterization and comparative analysis of toxin–antitoxin systems in Acetobacter pasteurianus

MicroRNA‐129‐1‐3p regulates cyclic stretch–induced endothelial progenitor cell differentiation by targeting Runx2

Regulation of Tip60‐dependent p53 acetylation in cell fate decision

Coexisting multi-stable patterns in memristor synapse-coupled Hopfield neural network with two neurons

Inductor-free multi-stable Chua’s circuit constructed by improved PI-type memristor emulator and active Sallen–Key high-pass filter

Coexisting multiple firing patterns in two adjacent neurons coupled by memristive electromagnetic induction

Convex formulation of multiple instance learning from positive and unlabeled bags

Double pincer movement: Encircling rupture splitting during the 2015 Mw 8.3 Illapel earthquake

Initial condition-dependent dynamics and transient period in memristor-based hypogenetic jerk system with four line equilibria

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