The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
An online neuro-robotic platform in the form of a small vehicle, the “RatCar” has been developed. First, a rat had neural electrodes implanted in the motor cortices to record extracellular potentials. Then, our system combined the rat and its vehicle body by hanging the rat under its floor. In this paper, an experimental platform is proposed to observe and analyze motor commands by correlating neural...
Identification, analysis, and treatment of potential risk in surgical workflow are the key to decrease medical errors in operating room. For the automatic analysis of recorded surgical information, this study reports multichannel audio visual recording system, and its review and analysis system. Motion in operating room is quantified using video file size without motion tracking. Conversation among...
In this study, we suggest a new guideline for regeneration microelectrode to be implanted between the severed stumps of peripheral nerves, the microelectrode designed particularly for connecting the signal line of an artificial hand directly to the nerve system. The nerve regeneration microelectrode is an interface device expected to realize a BMI (brain-machine interface). As the microelectrode device...
Gliomas represent the most frequent type of primary intracranial tumors, which originate from the brain tissue itself, have infiltrative growth, unclear borders, and usually affect functionally-important cerebral structures. From March 2000 till March 2010, 839 neurosurgical procedures directed on resection of such neoplasms were performed in the intelligent operating theater of Tokyo Women's Medical...
This paper describes a new sleep monitoring system for home use. The basic system consists of a wearable physiological sensor and the PC software for analyzing sleep quality from user's wrist motion and heart rate variability. Different from a conventional sleep monitoring device used in a hospital, the sensor is so small and easy-to-use that a normal person can use it at home. This means that the...
In recent years there has been an ever increasing amount of research and development of technologies and methods to improve the quality and the performance of advanced surgery. In other fields several training methods and metrics have been proposed, both to improve the surgeon's abilities and also to assess her/his skills. For neurosurgery, however, the extremely small movements and sizes involved...
In recent years there has been an ever increasing amount of research and development of technologies and methods to improve the quality and the performance of advanced surgery. In several fields, such as laparoscopy, various training methods and metrics have been proposed, both to improve the surgeon's abilities and also to assess her/his skills. For neurosurgery, however, the extremely small movements...
In this study we fabricate a cell-guide on a thin disc-shaped probe with numerous microholes to be implanted between the severed stumps of axons; the cell-guide directs the regenerating axons though the holes in our probe (Fig. 1(a)). Since cell growth is greatly influenced by the topography of the substrate [1-3] we design a SU8 microfluidic cell-guide with a particular shape (Fig. 1(b)) to prevent...
Antiphasic electromyographic (EMG) activities between biarticular arm muscles are indispensable for smooth performance. In the case of two-joint arm movement in a planar horizontal plane, elbow and shoulder joint movements were achieved by the biceps brachii (BB) and the triceps brachii muscles (TB). To our knowledge, however, no conclusions have been reached concerning the antiphasic EMG activities...
The present study introduces an approach to detecting and classifying the extracellular action potentials of neurons, a process usually referred to as spike sorting. Our approach is based on template matching which is an optimal filter under Gaussian noise. However, this is usually expensive in terms of computational time, and constructing appropriate templates can be also problematic. Despite its...
Two types of intracortical multichannel flexible neural probes coated with a hybrid biodegradable polymer were designed and fabricated. The hybrid biodegradable polymer was made of polyethylene glycol and biodegradable polymeric microspheres containing nerve growth factor (NGF) and incorporated to improve the stiffness for flexible neural probe insertion, and promote regrowth of damaged neural tissues...
We have developed a brain-machine interface (BMI) in the form of a small vehicle, which we call the RatCar. In this system, we implanted wire electrodes in the motor cortices of rat's brain to continuously record neural signals. We applied a linear model to estimate the locomotion state (e.g., speed and directions) of a rat using a weighted summation model for the neural firing rates. With this information,...
A flexible intracortical neural probe containing a biodegradable polymer for delivering bioactive components was developed. This was designed to promote regrowth of damaged neural tissues around the implanted neural probe for a long-term recording. The neural probe was based on the flexible and biocompatible material of parylene C incorporated a drug delivery system (DDS). A groove structure of the...
A prototype of a small vehicle controlled by the neural signals from the primary motor cortex of a rat's brain that we named 'RatCar' system has been developed. We implanted wire electrodes in the regions of a rat's brain that control the hind limbs to chronically record its neural signals. Next, we assumed a linear model to estimate the walking speed of a rat by the weighted firing rates in the primary...
In this paper, descriptions of various flexible neural probes and a rat car system, which we developed, are presented. The probe is sufficiently flexible to enable minimally invasive recording. Some of these probes have micro-fluidic channels integrated into the probe that can be used to inject chemicals into neural tissues and achieve a stable interface with the nervous system. The focus is on issues...
A flexible neural probe with micro-fluidic channels has been developed. The probe is sufficiently flexible to enable minimally invasive recording. The fluidic channel integrated on the probe is capable of injecting chemicals into neural tissues. In addition, it permits a stable interface with the nervous system. We focus on issues concerning: 1) stable recording with electrodes placed in fluidic channels,...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.