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This study proposes and evaluates a neural network (NN) classifier for dividing the histological structures (HS) in breast cancer (BC) microscopic image into two region types: cancer or normal. Cancer region included positive cells and negative cells while normal region included stromal cells and lymphocyte. The classification task using a back propagation learning algorithm is applied to the multilayer...
The improvement of heart function are the important consideration for heart failure patient with rotary blood pump (RBP). The capable of function evaluation depend on good monitoring system, which facilitate the physician for diagnosis. In this study, pressure estimation from measured flow rate for the patients with external RBP support is implemented with the non-invasive technique for cardiac function...
This article presents grounded inductance simulator using single current controlled current follower transconductance amplifier (CCCFTA) as active element. The simulated inductance value can be controlled electronically by adjusting the bias current of the CCCFTA. The grounded inductance simulator comprises one CCCFTA and one grounded capacitor without any external resistors and component matching...
This works introduces a wireless signal processing platform based on a low-power FPGA. The architecture of the circuit is customized for the processing of sensor data used in biomedical applications such as ECG, EEG, or activity recognition using wearable computing. Hardware accelerators can be dynamically reconfigured to implement multiple signal processing tasks in a time-multiplexed manner. This...
The research aimed to present airflow analysis of radiofrequency ablation for asthma therapy by using three-dimensional finite element method. We study a solution for asthma therapy by using radiofrequency ablation method. Airflow is main factor for asthma therapy. Asthma patients have shortness of breath, coughing, wheezing, and chest tightness that influence a daily life of patients. All symptoms...
Electrical stimulation is an important technology for medical devices; however, safely limiting the electric current injection is an issue that remains to be solved. To improve the electrical properties of electrodes, we have proposed the use of tubular membrane proteins for achieving intracellular stimulation. This electrode, called “proteoelectrode”, is designed to control membrane potential across...
Bone drilling by using heat energy from microwave is a promising research issue and has been proposed by some researcher. However, there are still some interesting topics remaining to be investigated especially in term of a temperature variation during burning or drilling process and a prediction of an extreme burning size or drilling diameter. In this paper, we propose an FEM investigation of bone...
Valvular heart disease is considered as an important problem of heart. The mechanical heart valve replacement is one of the methods used to treat valvular heart disease. There are many designs of mechanical heart valves including bileaflet and trileaflet valves. As the heart valve operates under the blood pressure conditions, it might be damaged or impaired. We aimed to design a trileaflet mechanical...
A challenge in using myoelectric signals in control of motorised prostheses is achieving effective signal pattern recognition and robust classification of intended motions. In this paper, the performance of Matlab's Multi-layer Perceptron (MLP) backpropogation training algorithms in motion classification were assessed. The test and evaluation platform used was “BioPatRec”, a Matlab-based open-source...
This paper focuses on a biomolecular detection method based on amplification and encoding with DNA reactions. For proof of the concept, we demonstrate that encoding of molecular signal with amplification is achievable using a hybridization chain reaction with fluorescence resonance energy transfer.
A pain is a human phenomenon when sensory receptors are stimulated by the injury. It can be caused from accident or intention. Everybody have this kind of sensation because the pain is a natural warning for react in order to protect a whole body. However, the reaction from the pain sometimes have to be avoid because the overreaction causes some damages to near-by tissue. An acute thermal pain is one...
Fluorescence anisotropy of GFP molecules, suspended in solution and immobilized on a glass substrate, was measured to investigate the application for nano-environment probe. Nano-environment around living cell is of interest in relation with wide range of fields, such as cell interaction in cancer tissue, nerve signal transmission and so on. However, nano-environment is so sensitive to the interference...
The effects of LED light at 635 nm in fibroblast and osteoblast were investigate in fundamental changes as preliminary experiment. In this study, primary gum fibroblast cells and osteoblast cell line were cultured. After LED light irradiation, we found that fibroblast growth rate and cell proliferation are increased after irradiated by 630nm LED light. Optimum energy for wound healing is 0.34 J/cm...
This article presents a proposal to measure the Bone Mineral Density (BMD) as a backup in the diagnosis of osteoporosis. An antenna arrangement, tuned to a frequency of general and medical use, is used to measure the relative attenuation of the signal on several samples of bovine bone, silica and bone powder. By implementing a Support Vector Machine (SVM) it is possible to establish patterns to classify...
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