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With the advent of precision medicine, biomarkers have recently come into focus as a promising tool for early cancer detection and treatment individualization. In particular, much interest has been shown in the oral microbiome as a promising potential cancer biomarker, especially for head and neck cancers. The American Cancer Society estimates that there will be nearly 50,000 new cases and roughly...
Drug-Drug Interaction (DDI) relation extraction is a multi-class classification problem that aims to predict the interaction between drugs in a sentence. The configuration of Convolutional Neural Network (CNN) in relation extraction usually applied shallow architecture layers, which may make the information in given input text is not fully captured, thus fail to capture a long sentence containing...
Automated segmentation of intracranial arteries on magnetic resonance angiography (MRA) allows for quantification of cerebrovascular features, which provides tools for understanding aging and pathophysiological adaptations of the cerebrovascular system. Using a convolutional autoencoder (CAE) for segmentation is promising as it takes advantage of the autoencoder structure in effective noise reduction...
Epileptic seizure detection has gained increasing attention in clinical therapy. Scalp electroencephalogram (EEG) analysis is a common way to capture brain abnormality for seizure onset detection. This paper presents a novel context-learning based approach using multi-feature fusion to compensate for incomplete description of single feature in epileptic EEG signals. First, EEG scalogram sequence is...
In biomedical research, events revealing complex relations between entities play an important role. Event trigger identification is a crucial and prerequisite step in the pipeline process of biomedical event extraction. There exist two main problems in the previous work: (1) Traditional feature-based methods often rely on human ingenuity, which is a time-consuming process. Though most representation-based...
In recent years, there has been explosive growth in the amount of biomedical publications. In this paper, we propose a semantic framework that aims to automatically generate an ontology by extracting assertions and topics from multiple free-text scientific publications in PubMed. The pipeline approach for knowledge discovery and ontology generation in the proposed framework has been implemented on...
The de novo assembly aims to reconstruct the genome of the unknown species. Many algorithms have been proposed for de novo assemblies. Due to problems of repetitive regions and sequencing errors, contigs usually contain a large amount of misassemblies. Consequently, the misassembly correction of contigs is a challenging and significant work, which receives considerable attentions from researchers...
Many real-world problems involve multi-view high-dimension-small-sample-size data analysis, such as multi-omics data. The combination of multi-view databases is supposed to provide a better biological significance. However, the multi-view data always contain noise and outlying entries that result in inaccurate and unreliable. It has become an urgent need how to effectively analyze these data. We proposed...
The use of RPE as a measure of Internal load has become a common methodology used in team sports owing to its low cost. The aim of this study was to build a machine learning process able to describe the players' RPE by the external load extracted from the GPS. In this paper, we propose a multidimensional approach to assess the RPE in professional soccer which is based on GPS measurements and machine...
Lung cancer is one of the most common types of cancer originated from malignant lung nodules. Early detection of lung nodule is key in prevention of lung cancer. In this paper, we developed an online content-based image retrieval (CBIR) system to assist novice radiologists in identifying lung nodules. The system takes advantages of cloud computing and deep learning to retrieve similar lung nodules...
As the use of the Internet grows every year, e-commerce's usage does as well. There is a tough competition between companies to be able to attract customers to use their services. The design of a website is crucial to retain a customer, and a retained client is more valuable over time, so understanding what attracts the attention of a potential client on a website is really important. This work proposes...
In this study, we have developed the video based risk recognition training tool with an eye tracking device and a motion sensor. We applied the tool on the risk recognition training in a construction company and extracted features in risk recognition of expert field overseers from their eyes and utterances during the training. As the results of the examinations, typical risk recognition processes...
Comparing images to recommend items from an image-inventory is a subject of continued interest. Added with the scalability of deep-learning architectures the once 'manual' job of hand-crafting features have been largely alleviated, and images can be compared according to features generated from a deep convolutional neural network. In this paper, we compare distance metrics (and divergences) to rank...
In this paper, we propose a new discriminative dictionary learning framework, called robust Label Embedding Projective Dictionary Learning (LE-PDL), for data classification. LE-PDL can learn a discriminative dictionary and the blockdiagonal representations without using the l0-norm or l1-norm sparsity regularization, since the l0 or l1-norm constraint on the coding coefficients used in the existing...
Power grids are critical infrastructure assets that face non-technical losses (NTL) such as electricity theft or faulty meters. NTL may range up to 40% of the total electricity distributed in emerging countries. Industrial NTL detection systems are still largely based on expert knowledge when deciding whether to carry out costly on-site inspections of customers. Electricity providers are reluctant...
Biomarkers have tremendous potential in different phases of treatment such as risk assessment, screening/detection, diagnosis and patient's response prediction. In this paper, we present an approach for development of a generic tool for an end to end analysis of expression data to identify the probable biomarkers. We follow machine learning as well as network analysis approaches in parallel. We use...
The bag of words (BOW) represents a corpus in a matrix whose elements are the frequency of words. However, each row in the matrix is a very high-dimensional sparse vector. Dimension reduction (DR) is a popular method to address sparsity and high-dimensionality issues. Among different strategies to develop DR method, Unsupervised Feature Transformation (UFT) is a popular strategy to map all words on...
Opioid (e.g., heroin and morphine) addiction has become one of the largest and deadliest epidemics in the United States. To combat such deadly epidemic, there is an urgent need for novel tools and methodologies to gain new insights into the behavioral processes of opioid addiction and treatment. In this paper, we design and develop an intelligent system named iOPU to automate the detection of opioid...
We treat failure prediction in a supervised learning framework using a convolutional neural network (CNN). Due to the nature of the problem, learning a CNN model on this kind of dataset is generally associated with three primary problems: 1) negative samples (indicating a healthy system) outnumber positives (indicating system failures) by a great margin; 2) implementation design often requires chopping...
Neural network based architectures used for sound recognition are usually adapted from other application domains such as image recognition, which may not harness the time-frequency representation of a signal. The ConditionaL Neural Networks (CLNN) and its extension the Masked ConditionaL Neural Networks (MCLNN) are designed for multidimensional temporal signal recognition. The CLNN is trained over...
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