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Biomarkers have tremendous potential in different phases of treatment such as risk assessment, screening/detection, diagnosis and patient's response prediction. In this paper, we present an approach for development of a generic tool for an end to end analysis of expression data to identify the probable biomarkers. We follow machine learning as well as network analysis approaches in parallel. We use...
Genome compaction is a universal feature of cells and has emerged as a global regulator of gene expression. Compaction is maintained by a multitude of architectural proteins, long non-coding RNAs (lncRNAs), and regulatory DNA. Each component comprises interlinked regulatory circuits that organize the genome in three-dimensional (3D) space to manage gene expression. In this review, we update the current...
The collection, detection and monitoring of information such as side effects, adverse effects, warnings, precautions of pharmaceutical products is a challenging task. With the advent of user forums, online reviews have become a significant source of information about products. In this work, we aim to utilize pharmaceutical drugs reviews by patients on various health communities to identify frequently...
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