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A general method for coupling individual living cells to computers is presented. This method is called visual-servoing optical microscopy?? (VSOM??). Protocols, instrumentation, and software are described and experimental results are presented. During VSOM experiments, automated decisions are made as single cell responses to computer-applied stimuli are interpreted in real-time. Well-annotated live...
The microscopic analysis of time dependent 3D live cells provides considerable challenges to visualization. Effective visualization can provide insight into the structure and functioning of living cells. The paper presents a case study in which a number of visualization techniques were applied to analyze a specific problem in cell biology: the condensation and de-condensation of chromosomes during...
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