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The simplified and genetically conserved zebrafish pronephros is an excellent model to examine the cryptic processes of cell fate decisions during the development of nephron segments as well as the origins of associated endocrine cells that comprise the corpuscles of Stannius (CS). Using whole mount in situ hybridization, we found that transcripts of the zebrafish genes t-box 2a (tbx2a) and t-box...
We discuss current progress towards two complementary web resources being developed for the Renal Physiome: (1) a database (QKDB) for quantitative and anatomical data at all levels of kidney organization, including molecular-level information on membrane channels and transporters, structural and functional parameter values at the epithelial level, measured flows and concentrations along vessels and...
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