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In the present work, we prepare and evaluate a cell-based microrobot for active drug delivery to tumors. The microrobots are fabricated using the engulfment activity of immune macrophages with drug-loaded magnetic liposomes (MNP-DLs) via phagocytosis. The synthesized MNP-DLs and the microrobots have high energy absorbance to NIR light with increased drug release rate after laser irradiation. The tumor...
In this study, we prepare and evaluate a novel cellbased micro-platform (microrobot) for active tumor therapy. The microrobots are fabricated utilizing the engulfment activity of immune cells (macrophages) with drug-loaded magnetic liposomes via phagocytosis. First, we synthesize magnetic nanoparticles (MNP) with superparamagnetic properties and high energy absorbance to near-infrared (NIR) light,...
At present, microrobots have been utilized as useful tools in diagnosis and treatment of various human diseases. As a new alternative for Chronic total occlusion (CTO), researchers are developing a intravascular therapeutic microrobot system by controlling the movement of the microrobot outside the patient's body, and using an electromagnetic actuation (EMA) system to increase the accuracy of therapy...
In this paper, a novel hybrid Three-Redundant Electro-Mechanical Actuator (EMA) system is proposed, which is mainly composed of two automatic brushless DC motor (BLDCM) drivers and one manual BLDCM driver. Each driver is in charge of the control of one brushless DC motor. At any tine, only one set of drivers works to realize the accurate position control. The rationality of the system is analysed...
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