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Deterministic multi-layer micro-scale assembly of SU-8 polymer objects as well as the cohesively joined SU-8 interface strength have been investigated. The process of SU-8 photoresist (PR) into retrievable individual micro-scale objects format called “ink” is reviewed and the construction of three-dimensional (3D) unique micro-structures via micro-Lego, which refers to the transfer printing of the...
Samples of thermally controlled shape memory alloy (SMA) composite nanotweezers based on bilayered structures Ti2NiCu/Pt with dimensions (0.8–30)×(0.1–10)×(0.07–2)μm have been developed. Each of these composites could be used to create the smallest miniature devices to date for micro- and nanomechanics, fluidics, electronics, medicine and S&A technologies. It was found that the reversible deformation...
Capsule endoscopes (CEs) have been highlighted as a next generation diagnostic device for the digestive organs (i.e. the stomach, small bowel and colon). Although CE imaging functions and control techniques have been continuously studied, CEs cannot completely replace conventional wire-based endoscopes because current commercial CEs only have diagnosis functions. To extend the range of applications...
In this paper, a method based on an oscillating flow consisting of an 8 Hz vibrating flow and a constant flow used to increase the manipulation capability of particles in liquid is developed and demonstrated. The method was integrated with magnetic resonance navigation (MRN) for targeted manipulation. Micro particles encapsulating superparamagnetic nanoparticles were successfully navigated in a Y-shaped...
We report memristive device characterization using near-field scanning microwave microscopy. Atomic force microscopy, magnitude and phase-shift images of the complex reflection coefficient of TiO2 devices can be acquired simultaneously in the range 1-20 GHz. In particular, measurement of the complex reflection coefficient of a 200 by 200 nm2 TiO2 device is exemplary demonstrated. These results are...
Laser die transfer technique provides an efficient solution for fast transportation of microchips in microassembly. Capillary self-alignment is able to achieve parallel and high-accuracy alignment of microchips on receptor sites. In this paper, we propose a new hybrid microassembly strategy, which combines laser die transfer and capillary self-alignment techniques. The laser die transfer technique...
Laser is a very unique and useful tool for materials processing with the various parameter choice range. The main mechanism of typical laser processes is photo-induced thermal reaction that generates confined temperature field at a desired position with high controllability. The laser-induced selective temperature rise enables selective chemical reaction for synthesis of nanomaterials in various environment...
In this study, we demonstrate the functionality and usability of a compact, pneumatically actuated, elastomeric stimulation device for mechanobiological studies. The soft mechatronic device enables high-resolution live-cell confocal fluorescent imaging during equiaxial stretching. Several single cells can be tracked and imaged repeatedly after stretching periods. For demonstration, we provide image...
Robotic swarm designers aim to increase the functionality of their swarms while maintaining the lowest possible cost of the individual robots. This usually results in robots with very limited sensing and computing capabilities. These limited capabilities make it necessary to develop algorithms and methodologies to enable the robots to perform tasks such as tracking, following, and navigation functions...
MC-1 strain magneto-aerotactic bacteria recently used in cancer therapy and labeled with superparamagnetic nanoparticles are localized by magnetic particle imaging (MPI) spectrometry. A 8.5 mT drive field oscillating at 150 kHz is generated in a solenoid coil and placed near two receiving coils connected in series in a gradiometric configuration. The magnetic behavior of superparamagnetic particles...
Intravenous systemic injection of fluidMAG-PMO magnetic nanoparticles followed by hyperthermia of the brain has previously shown to be a promising method for overcoming the blood-brain barrier; the great challenge of drug delivery to the brain. This study explores the possibility of utilizing magnetotactic bacteria as micro-carriers for fluidMAG-ARA magnetic nanoparticles as means of direct targeting...
The preponderance of research into flying microrobots has focused on biomimetic flight mechanisms. In this work, we demonstrate an insect-scale robot capable of vertical takeoff using electrohydrodynamic thrust, a mechanism with no natural analogue. The 10mg, 1.8cm by 1.8cm “ionocraft” operates at about 2400 volts and has a thrust to weight ratio of approximately 10. Feasibility of using individually...
In this work, Scanning Microwave Microscopy (SMM) is applied to breast cancer cells MCF-7 treated by fullerene (C60), in order to provide simultaneous topographic and electromagnetic characterization of sample surface. The exceptional properties of fullerene, like its lipophilicity and its ability to be functionalized with proteins and nucleic acids, make its use very promising for drug delivery and...
This paper presents a new optimization-based method to control three micro-scale magnetic agents operating in close proximity to each other for applications in microrobotics. Controlling multiple magnetic microrobots close to each other is difficult due to magnetic interactions between the agents, and here we seek to control those interactions for the creation of desired multi-agent formations. Our...
Nowadays, cells are commonly used for predicting whether the drug compounds will be effective and safe in human. The response of cell groups was usually analyzed, instead of single cell. However, individual cells within the same population even shows various characteristics. Understanding this heterogeneity is critical to studying how effective therapies will be in the clinic. Therefore, highly efficient...
This paper presents two mechanisms to enable jumping microrobots. These small jumpers must store considerable mechanical energy and quickly release it. The first mechanism presented is a mechanical gain stage capable of amplifying the force generated by a standard inchworm motor by at least 10 times. This mechanism could be used with any style of inchworm motor. Secondly, a latching mechanism was...
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