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Treatment of renal cell carcinoma (RCC) using ablation techniques is becoming increasingly common as a means for preserving renal function in poor surgical candidates. Despite concerns related to renal insufficiency, which is common in patients with renal disease, the current standard for imaging surveillance following ablation remains contrast-enhanced CT or MRI. Contrast-enhanced ultrasound (CEUS)...
Objective To discuss the clinical diagnosis value of Multislice helical CT in renal cell carcinoma (RCC) and angiomyolipomas (AML). Methods 93 patients (78 were RCC and 15 were AML by pathologic diagnosis through postoperative examination of specimen) were retrospectively analyzed. CT number in ROI (region of interest) of these masses was recorded, CT number in ROW (region of whole mass) of these...
Color variation in medical images degrades the classification performance of computer aided diagnosis systems. Traditionally, color segmentation algorithms mitigate this variability and improve performance. However, consistent and robust segmentation remains an open research problem. In this study, we avoid the tenuous phase of color segmentation by adapting a bag-of-features approach using scale...
The task of analyzing tissue biopsies performed by a pathologist is challenging and time consuming. It suffers from intra- and inter-user variability. Computer assisted diagnosis (CAD) helps to reduce such variations and speed up the diagnostic process. In this paper, we propose an automatic computer assisted diagnostic system for renal cell carcinoma subtype classification using scale invariant features...
In this paper we present the results of our effort to develop a computer aided diagnosis system for pathological imaging data using renal cell carcinoma as a case study. Traditionally, cancer diagnosis is performed by an expert pathologist studying biopsy tissue under a microscope. Due to the complex nature of the task and the heterogeneity of patient tissue, these methods are not only time consuming...
As a minimally invasive alternative to current treatment of renal cell carcinoma, the use of superheated liquid perfluorocarbon droplets encased in albumin shells has been proposed to treat cancer by occlusion therapy. In response to an applied acoustic field, these droplets, which are small enough to pass through capillaries, vaporize into large gas bubbles that subsequently lodge in the vasculature...
Identification of genetic markers is a crucial step in the diagnosis, prognosis, and treatment of disease. This paper focuses on the application of a supervised classification technique, support vector machines (SVM), to high dimensional microarrays for marker identification. A case study of renal cell carcinoma (RCC) is used here to demonstrate and test the ability of SVMs to identify real biological...
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