The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
By controlling spike timing and sculpting neuronal rhythms, inhibitory interneurons play a key role in brain function. GABAergic interneurons are highly diverse. The respective GABAA receptor subtypes, therefore, provide new opportunities not only for understanding GABA-dependent pathophysiologies but also for targeting of selective neuronal circuits by drugs. The pharmacological relevance of GABA...
According to the UN World Health Organization, nearly one in every six of the world's population is affected by a neurological disorder. This research study focused on neural networks and analyzed the connections between neurological disorders defined by similar single nucleotide polymorphisms (SNP). By utilizing the Genome-wide Association studies, SNPs associated with a select group of neurological...
This chapter presents case studies for epilepsy, dementia, eating and drinking, sleep, women's issues, sexual disorders, ASD, ADHD, aggression, self‐injurious behaviours, anxiety, depression, bipolar, schizophrenia, alcohol, and personality disorder. These case studies suggest the diagnostic possibilities and management of all these disabilities. In the case of dementia, the chapter highlights that...
The prevalence of schizophrenia in the general population is between 2.5 and 5.3 per 1000. In the intellectual disability (ID) population, the prevalence of schizophrenia depends on the nature of the study sample and has commonly been quoted at around 3%. The prevalence of schizophrenia is reported to be highest in those with a mild degree of ID. The reason for this may be contributed to by several...
A standard segmentation problem within Magnetic Resonance Imaging (MRI) is the task of labelling voxels according to their tissue type that are White Matter (WM), Gray Matter (GM), and Cerebrospinal fluid (CSF).Image segmentation provides volumetric quantification of cortical atrophy and thus helps in the diagnosis of degenerative diseases such as Epilepsy, Schizophrenia, Alzheimer's disease, Dementia...
Computer-assistance has reached virtually every domain within the field of medical imaging. But, even after four decades of intensive medical image analysis research, most of the fully automated methods have not been adopted for clinical routine use. Dedicated computer aided-diagnosis tools with proven clinical impact exist for a narrow range of applications, including mammography and chest imaging,...
The electroencephalogram is an attractive clinical tool given its non-invasive nature, its ability to reflect real-time changes in local cortical activity, and the load of objective bioelectrical measurements that can be derived from it. For decades, the electroencephalogram has been successfully used for diagnosing epilepsy and schizophrenia, among other brain disorders. This paper focuses in the...
Neurobiologists are interested in understanding how neurons form complex synaptic circuits during development and how these processes are perturbed in neuropathies. It has been well established that neuronal migration and maturation during development play a critical role in how neurons ultimately function. To better understand these two key features of mammalian neurogenesis, neurobiology researchers...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.