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Mercuric ion (Hg2+) has been found to increase coagulant activity in whole blood. We conducted an in vitro study to determine whether mercuric chloride (HgCl2) has an effect on blood coagulation when added to whole blood solutions containing either PT or APTT reagent. We used 10 mul of 10% PT reagent and 10 mul of 10% APTT reagent and added them to separate solutions of 990 mul of human citrated whole...
Several in vitro studies have employed ultrasonic techniques to detect varying properties of coagulating blood under static or stirred conditions. Most of those studies mainly addressed on the development and feasibility of modalities and however were not fully considering the effect of blood flow. To better elucidate this issue, ultrasonic backscattering were measured from the coagulating porcine...
In previous studies [Ossant, et. al., 2004; Libgot, et. al., 2005], we presented a device capable to simultaneously estimate, during the blood clotting process, HF ultrasound parameters both in double-transmission mode (DT-mode) and in backscattering mode (BS-mode). The integrated BS coefficient (IBC) and the effective scatterer size (ESS) were evaluated between 10 and 30 MHz. In DT-mode, sound velocity...
Most of previous investigations on the evaluation of blood coagulation were performed from the blood under static or stirred conditions which however are far from those of in vivo cases. Hence, this study is to detect varying properties of clotting blood through ultrasonic statistical model calculated from backscattered signals under steady flow condition at a 40 s-1 mean shear rate. The radiofrequency...
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