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Collagen is believed to be one of the principal load bearing components of skin. This implies that deformation of collagen microfibrils play an important role in determining the extent of skin deformation under applied loads. We have developed a novel technique for generating internal strain maps of bundles of collagen microfibrils in the skin. The technique relies on digital image correlation (DIC)...
Collagen fibrils contribute to the structural integrity and crack resistance of bone, but their response to stress while in bundles of fibrils is not well known. Digital image correlation (DIC) is a powerful technique for measuring strain by comparing images of deformed samples to non-deformed samples, while second harmonic generation microscopy (SHGM) captures bright, high contrast images of bone...
Atherosclerotic change of the arterial wall leads to a significant change in its elasticity. For assessment of elasticity, measurement of arterial wall deformation is required. For motion estimation, correlation techniques are widely used, and we have developed a phase-sensitive correlation method, namely, the phased-tracking method, to measure the regional strain of the arterial wall due to the heartbeat...
Ultrasound strain imaging maps the tissue stiffness in the region of interest by estimating strain when the tissue is stressed. Prestress and poststress ultrasound echoes are processed to estimate the displacements, and the strain image is computed by a spatial derivative of the estimated displacement. Due to the nature of derivative operations, smaller errors in displacement estimation can cause...
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