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Applications of optical spectroscopy techniques, such as Fourier Transform Infrared (FTIR), Raman, and fluorescence, in biology and medicine have been actively pursued in recent times. Since optical spectroscopic techniques are very sensitive to biochemical composition of the sample under study, they are being pursued as non invasive analytical methodologies. Early transformation from healthy to diseased...
Many machine learning technique have been employed for the classification of biological cells based on their Raman spectroscopy. Unfortunately, Raman spectroscopy data always has so many attributes that people who deal with them may often confront the problem of "curse of dimensionality". PCA is often used as a linear dimensionality reduction technique for preprocessing Raman data, which...
A rapid trapping and detection method for clinical bacteria (Helicobacter pylori, H. pylori) analysis is designed and reported in this study. Different strain of H. pylori can be trapped in 3 dimension dielectrophoresis chip (DEP) under the condition of 20 mM PBS, voltage at 20 Vp-p and frequency at 300 kHz. H. pylori #238(Wild type) presents more and stronger functional group stretching and vibration...
Laser-induced fluorescence and Raman spectroscopy of serum for detect colon cancer was investigated in this paper. The difference to serum spectrum was discovered. Three Raman peaks were consistently observed from normal blood serum emission using 488.0 nm and 514.5 nm excitation of an Ar-ion laser. While no Raman peak or slight Raman peaks were detected from colon cancer's cases. In addition, the...
Laser-induced fluorescence spectroscopy (LIF) and Raman spectrum of serum for diagnosis of rectum cancer were investigated by criteria of three parametric modes in this paper. The aim of this study was in an attempt to find the difference normal and rectum cancer cases, therefore 89 rectum cancer samples were measured using fluorescence and Raman spectrum. The experimental result showed that there...
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