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We have demonstrated that carbon-nanotube field-effect transistors act as highly sensitive single-molecule detectors when point functionalized. The hybridization kinetics of two complementary strands of DNA are associated with two-level fluctuations in the conductance of the nanotube to which the DNA is bound. We have studied the temperature dependence of the nanotube conductance and shown that the...
In this study, the authors propose a new bacteria detection method using a carbon nanotube (CNT) gas sensor and a microheater, which were coupled into a Bio-MEMS (microelectromechanical systems)-type device. Bacteria were heated by the microheater in air so that ammonia (NH3) gas can be generated by the oxidation reaction of organic components of bacteria. Thus generated NH3 gas was detected by using...
We present ion-sensitive conductometric glucose sensors prepared by layer-by-layer (LbL) nano self-assembly of single-walled carbon nanotube (SWNT) and enzyme glucose oxidase (GOx). The carboxylated SWNT and GOx are self-assembled alternatively with a positively charged polyelectrolyte, poly(diallyldimethylammonium chloride, PDDA). Quartz crystal microbalance (QCM) study and Fourier transform infrared...
Electrochemical detection is a promising technique for bio-analytes sensing because of rapid analysis, good selectivity, reusability, thermal stability, linearity and relatively low cost. There have been consistent efforts to improve the performance of the electrochemical biosensors which include functionalization of the working electrode surface by polymer or nanomaterials. In this work, a cholesterol...
Electrochemical properties of double wall carbon nanotubes (DWCNT) were assessed. The biosensing utility of f-DWCNT film electrodes was probed by using cyclic voltammetry and amperometry of NADH and glucose. Enzyme glucose oxidase (GOx) was used as non-covalent modifier of surface of f-double wall carbon nanotubes and such assembly was used for construction of electrochemical binder-less glucose biosensor...
Significant research and development efforts have been devoted to producing reliable glucose sensors for in vitro or in vivo applications, because of high demand for blood glucose monitoring and other application. The outstanding electrochemical properties of carbon nanotubes, along with their high surface area, can promote electron-transfer and enlarge enzyme loading, which provide the available...
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