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Spontaneously hypertensive rats (SHR) represent an animal model of cognitive decline associated with hypertension. Few studies have systematically investigated this decline in aging. We assessed spatial learning performances of SHR, the genetically similar Wistar-Kyoto rats (WKY), and Sprague-Dawley rats (SD), in a water maze (WM) task. The following age ranges were studied: 6, 12, and 20 months....
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