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The purpose of this study was to investigate whether stress sensitivity mediates the relationship between traumatic life events and total attenuated positive psychotic symptoms, as well as the relationship between traumatic life events and endorsement of 8 or more attenuated positive psychotic symptoms as distressing (a threshold that has been associated with higher risk for psychosis in clinical...
A combination of early neurodevelopmental disruptions and young-adult cannabis use may lead to the development of neuropsychiatric disorders. The aim of this study was to investigate in adult Wistar rats (12–14 weeks of age) the long-term ‘two hit’ behavioural effects of chronic young-adult treatment with the cannabinoid receptor agonist, CP55,940 (0.2mg/kg, 8–10 weeks of age) in combination with...
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