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Summary Fracture risk prediction can be enhanced by the concurrent assessment of other clinical risk factors. This study demonstrates that the estimation of an individual’s 10-year probability of fracture by the FRAX® algorithm identifies patients at high risk of fracture who will respond to bisphosphonate therapy. Introduction Treatments for osteoporosis are targeted largely to patients with low...
Summary Fall risk does not significantly impact on the efficacy of the bisphosphonate clodronate in reducing the incidence of fracture. Introduction The debate about the efficacy of skeletal therapies on fracture risk in women at increased risk of falling continues. We determined whether fall risk impeded the efficacy of clodronate to reduce osteoporotic fracture incidence. Methods This is a post...
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