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Science is facing a new RNA world that is shaping our knowledge, and we are discovering a new horizon in molecular biology. New technologies revealed thousands and thousands of new RNAs, most of them located in what was once known as the “dark matter of DNA”. They are functional regulatory RNAs and do not code for proteins, and they orchestrate the cellular function according to the changes needed...
Recent experimental evidence suggests that most of the genome is transcribed into non‐coding RNAs. The initial transcripts undergo further processing generating shorter, metabolically stable RNAs with diverse functions. Small nucleolar RNAs (snoRNAs) are non‐coding RNAs that modify rRNAs, tRNAs, and snRNAs that were considered stable. We review evidence that snoRNAs undergo further processing. High‐throughput...
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