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We are seeking ground-truth 3D X-ray CT phantoms with gradations of Hounsfield units that are indistinguishable from scans of human subjects. We modified a 3D printer, a ZCorp Spectrum 510, adding an iodine-based contrast agent, and printed physical models using a powder which consists mainly of cellulose and cornstarch. We scanned these 3D models with a Siemens Somatom Definition AS 128-slice CT...
The purpose of this preclinical study was to use an in vivo tumor-mimic model on pig liver for evaluating the accuracy of large HIFU ablations as required for human treatments. Tumor-mimics were created in in vivo porcine livers by injecting a 1 cc warm mixture of agarose, cellulose, glycerol and methylene blue, which formed 1 cm hyperechoic discrete lesions on sonograms. Three studies were conducted:...
In many applications, high intensity focused ultrasound (HIFU) treatments are guided using ultrasound imaging. To date, efficacy of ablative technologies such as HIFU for the treatment of liver tumor has been studied in animal models without any tumor or in small animals like rat and rabbit with established tumor. The purpose of this study was to use an in vivo tumour-mimic model for guiding HIFU...
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