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In recent times, there is an intense need for a reliable non-invasive diabetes prediction system. Some of the researches in this field suggest that acetone gas in breath has a good correlation to blood glucose levels. Hence, acetone is emerging as a promising bio-marker in diabetes prediction. In this study, acetone levels are measured using quartz crystal microbalance sensor that has wide-scale application...
Currently emerging intracortical biosensing devices are promising alternative to allow studying the neural activity underlying cognitive functions and pathologies, understanding neurons interactions, locating onset seizures, detecting mind driven decisions, etc. This talk covers low-power analog circuits and packaging techniques used for the design and integration of biosensing Microsystems. Such...
The recent years have been marked by a surge of interdisciplinary collaborations among scientists, engineers, researchers, and medical practitioners focused on solving complex problems in medicine and related fields. These activities have resulted in the development of bio-inspired silicon, neural prosthetics, image processing systems, sensors and intravenous drug delivery devices that support diagnosis,...
Gateless AlGaN/GaN high electron mobility transistors (HEMTs) has some advantages include rapid response, low noise, and superior sensitivity. In different Al content, the Al0.3Ga0.7N has the excellent performance among Al0.17Ga0.83N and Al0.25Ga0.75N, and the performance can be achieved about -0.923 mA/mm-pH during pH 4-10, and -2.24 mA/mm-pH during pH 7-8. The result indicates that the better performance...
This paper introduces Chemical Bionics in which the biochemical physiology of cells in the body are implemented in VLSI to make novel bio-inspired therapeutic devices. As an example, the glucose dependant electrophysiology of the pancreatic beta cell is implemented in silicon to form a novel bio-inspired prosthetic for glucose homeostasis of Type I diabetes. For this, the Ion Sensitive Field Effect...
This paper discusses a 3-D heterogeneous system on a chip (3-D HSoC) for an important biomedical application. Specifically, it discusses the application for detecting and filtering infected cells in blood. For example, leukemia and HIV produce diseased cells that circulate in the blood stream and are characterized by certain surface proteins. If the sensor plane of the 3-D HSoC is coated with an array...
This study reports the phase detection of the two-port flexural plate wave (FPW) sensor for designing and integrating the miniature system and provides a comprehensive methodology for portable using in the biosensor applications of severe acute respiratory syndrome coronavirus (SARS-CoV). The miniature system mainly utilizes the concept of the frequency divider that involves a divider, a time-based...
One of the important factors determining the sensitivity of any biosensing system is successful integration of bio- molecular transducers with peripheral signal processing circuitry. In this paper we present an architecture of a multi-array biosensor that integrates molecular bio-wires based immunosensor with a multi-channel potentiostat array. The biosensor operates by converting binding events between...
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