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An advance technique combined nano-TiO2 photodynamic with immunity and electroporation methods performs high efficiency for photokilling LoVo cancer cells even at very low concentration (3.12 μg/ml). The results showed that LoVo cells could be killed completely within 30 min using this method. The mechanism of this process was investigated using confocal flourescent microscopy, TEM and comet assay...
Malignant gliomas are associated with poor prognosis. Photodynamic therapy (PDT), relying on light-activated toxicity of a photosensitizer, has been investigated as a means for improving patient survival. This review presents a summary of clinical results obtained with PDT using different photosensitizers for treating brain malignancies. Particular emphasis is on the use of 5-aminolevulinic acid (ALA)...
Flourescence resonance energy transfer (FRET) between CdSe quantum dots (QDs) and meso-tetraphenylporphyrin (TPP) photosensitizers is studied by two-photon excitation fluorescent spectroscopy with 800nm femtosecond laser pulses. Evident transfer results are obtained in both the steady-state and time-resolved experiments. A slight peak shift to the red region in the emission of the CdSe QDs is observed...
Hematoporphyrin monomethyl ether (HMME) that is the second generation photosensitizers is a new and promising porphyrin related photosensitizer for photodynamic therapy and diagnosis in certain tumor. The binding of HMME to bovine serum albumin (BSA) in aqueous solution was studied using fluorescence spectra and absorption spectra. It was shown that HMME has a powerful ability to quench the BSA fluorescence...
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