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Due to cyclic heart compressions, blood inside the vascular system is forwarded batch-wise. As a result, pulse waves propagate along the arterial vessel walls and are reflected on peripheral capillaries. The reflected pulses interfere with the incoming ones and cause a resulting pulse wave with a characteristic second peak. The shape of this pulse wave depends on the stiffness of the arterial wall,...
The measurement of multi-component temporal blood velocity and shear stress distributions in the cardiovascular system is important in hemodynamic evaluation of patients with various cardiovascular diseases since changes in local flow patterns may reflect development and progression of pathology. Here, we report on a custom designed echo particle image velocimetry (Echo PIV) system, with improved...
Recent research has shown that targeted ultrasound contrast microbubbles achieve specific adhesion to regions of intravascular pathology, but not in areas of high flow. It has been suggested that acoustic radiation can be used to force free-stream microbubbles toward the target, but this has not been verified for actual targeted contrast agents. We present evidence that acoustic radiation indeed increases...
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