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Targeted albumin shelled microbubbles (MBs) have been applied as a potential drug carrier for the treatment of cancer cells. To provide the pharmacokinetics of the targeted albumin MBs for in vivo therapeutic use of cancer therapy, the multimodality N-succinimidyl-4- [18F]fluorobenzoate (18F-SFB) labeled tumor angiogenesis-related vascular endothelial growth factor receptor 2 (VEGFR2) targeted MBs...
To elucidate the impacts of member of transcription factor AP-2(alpha,beta or y) on survivin gene expression in cancer cells and to provide a theoretical base for targeted suppression of survivin gene in tumor cells, the survivin core promoter pLuc- 230 and one of AP-2 member expression vectors (alpha,beta or y ) or control empty vector were cotransfected into Hela cells to detect the impacts of AP-2...
In this paper, we proposed a polysilicon (poly-Si) wire based biosensor for the detection of glucose and matrix metalloproteinase (MMP) extracted from cancer cells. A focus-ion-beam (FIB) processed capillary atomic-force-microscopy (C-AFM) tip was used to help for transferring trace amount of glucose and MMP solutions onto the exact position of the surface of the poly-Si wire sensor. Glucose solution...
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