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An inductively powered 32-channel wireless integrated neural recording system, capable of endless recording from small freely behaving animals, is reported. A power scheduling mechanism maintains the power consumption of the LNAs constant regardless of the number of channels. Closed-loop power transmission maintains the received power constant despite animal movements.
To analyze an abnormal gait pattern in mutant mice (Hugger), we conducted coarse-grained motion capture. Using a simple retroreflective marker-based approach, we could detect high-resolution mutant-specific gait patterns. The phenotypic gait patterns are caused by extreme vertical motion of limbs, revealing inefficient motor functions. To elucidate the inefficiency, we developed a musculoskeletal...
This paper presents the design of versatile platform for advanced neuroscience on the high-level brain functions and neural prostheses. The platform enables researchers to record and stimulate brain activities of multiple free behaving animals wirelessly. The platform consists of three major functional blocks of neural interface, wireless communication system, and neural signal processing software,...
With the extraordinary navigational ability in large-scale space, homing pigeons have been a valuable model to investigate the neurophysiological substrate of large-scale spatial cognition. Here we show a miniature chronic recording system that can be mounted on the back of freely behaving pigeons. In this paper, we mainly focus on the design and implementation of the head stage comprised of an instrument...
A growing number of brain-machine interfaces have now been developed that allow movements of an external device to be controlled using recordings from the brain. This work has been undertaken with a number of different animal models, as well as several human patients with quadriplegia. The resulting movements, whether of computer cursors or robotic limbs, remain quite slow and unstable compared to...
A computer program is presented which was developed to quantify and analyze evoked extracellular field potential (EEFP) waveforms, generated in the granule cell layer of the dentate gyrus, as a result of perforant path stimulation. The software extracts information from the EEFP, which is of extreme importance to neuroscience in determining synaptic and cellular plasticity in the rat hippocampus....
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