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Confluent monolayers of cells in culture media are usually fragile and are susceptible to mechanical disruption. To assess the growth and migration of the cells towards recovery, the mechanical disruption is often done deliberately to perform wound healing assay. In such analysis, after a scratch in the cell monolayer, electrical characterization has been done to provide related quantitative description...
Cellular based biosensing can serve as an effective method for detection of unknown toxins by monitoring cellular response. Electric cell-substrate impedance sensing (ECIS) does this by measuring the impedance of a cell monolayer grown on interdigitated gold electrodes. This is done in situ and in real time without disrupting the monolayer. As the monolayer settles and grows to confluence an increase...
Investigation of electrical properties along with molecular expressions of the keratinocyte and fibroblast under different physiological conditions can provide insight into their functioning which can contribute significantly towards skin tissue engineering application. For electrical characterization, cell based biosensors are usually designed with photolithographically patterned electrodes which...
The object of electrical bioimpedance measurement is the impedance or impedance changes of biologic tissue. The electrode used in electrical bioimpedance measurement works under AC stimulation, the electrode impedances of both DC and AC, the stability of them are much important. AC and DC impedance properties of four kinds of one-off Ag/AgCl ECG electrodes produced by different manufactories, and...
The design of a complementary metal-oxide-semiconductor (CMOS) integrated circuit that has the capability of evaluating the electrode-tissue contact and the lead functionality of implanted electrodes in neuroprostheses for functional electrical stimulation applications is presented. The system allows in a quite simple way the verification of the state of the electrode by the evaluation of its impedance...
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