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Cardiac function is reduced after acute myocardial infarction due to myocardial injury and to changes in the viable non-ischemic myocardium, a process known as cardiac remodeling. Current treatment of patients with acute myocardial infarction (AMI) reduces infarct size, preserves left ventricular function, and improves survival. However, it does not prevent remodeling which leads to heart failure...
To investigate the effects of NGF(Nerve Growth Factor) pretreatment on density of new vessels of acute myocardial infaction in rats. 60 male adult Wistar rats were randomly classified into three groups: the control (n=20), non-NGF (n=20) and NGF(n=20) groups. The NGF group was injected NGF (0.5μg/kg) via caudal vena. Then we performed left anterior descending coronary artery(LAD) ligation, all the...
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