The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
The recognized significance of rumen microbiome has inspired efforts to examine the composition of rumen microbial communities in a large scale. One of the key research areas is to infer association and dependencies between members of rumen microbial communities through correlation analysis. However, it has been found that due to the compositional nature of data, simply applying correlation-based...
Human studies aimed at opening the blood brain barrier (BBB) to deliver therapeutic agents through a combination of focused ultrasound (US) and microbubbles (MB) are currently underway [1]. Our goal was to develop an US-guided BBB opening system capable of steering the US beam throughout the rodent brain and registering the coordinates with high field MRI. Our ultimate goal is to deliver therapy for...
Extracellular matrix (ECM) proteins play a major role in the tissues of multicellular organisms. The ECM presents structural support for cells inside a tumor. Meanwhile, it also works homeostatically to mediate the interaction between cells. However, the current bioinformatics tools to predict the ECM proteins seem often fail. This paper introduces a method for predicting the ECM proteins from the...
In this paper, we propose a novel hybrid binary animal migration optimization (BAMO) with k-nearest neighbor approach (KNN) to predict apoptosis protein sequences using statistical factors and dipeptide composition. Binary animal migration optimization is used for selecting a near-optimal subset of informative features that is most relevant for the classification. K-nearest neighbor approach is used...
Cochlear implants operate within a bony channel of the cochlea, bathed in a fluid known as the perilymph. The perilymph is a complex fluid containing ions and proteins, which are known to actively interact with metallic electrodes. To improve our understanding of how cochlear implant performance varies in preclinical in vivo studies in comparison to human trials and patient outcomes, the protein composition...
Inadequate replacement of lost ventricular myocardium from myocardial infarction leads to heart failure. Investigating the regenerative capacity of mammalian hearts represents an emerging direction for tissue engineering and cell-based therapy. Recent advances in stem cells hold promise to restore cardiac functions. However, embryonic or induced pluripotent stem cell-derived cardiomyocytes lack functional...
Neuroscientists are using virtual reality systems, combined with other advances such as new molecular genetic tools and brain-recording technologies, to reveal how neuronal circuits process and act on visual information. The Web extra at http://youtu.be/e_BxdbNidyQ is an overview video showing the FlyVR system in operation, including four example experiments.
Secreted proteins play important roles in eukaryotes across each of the kingdoms of fungi, animals, plants and protists. The majority of secreted proteins are signal peptide dependent proteins so their prediction relies on the SignalP family of predictors for signal peptides. The recent release of SignalP 4.0 prompts the question of its impact on the prediction of secreted proteins when compared to...
Ribosomal protein L10A is a component of the 60S large ribosomal subunit. To explore the structure feature of RPL10A gene of the Ailuropoda melanoleuca,the cDNA and the genomic sequence of RPL10A gene were cloned using RT-PCR and touchdown -PCR technology. The obtained cDNA of RPL10A in giant panda is 689 bp in size, containing an ORF of 654 bp, and the deduced protein was composed of 217 amino acids...
Eimeria ten Ella is a major cause of coccidiosis in chickens, which can lead to serious economic impact on poultry production worldwide. Developing a cost effective sub-unit vaccine may be helpful to decrease loss in the poultry enterprise. Here, we describe expressing etMIC4, which is one of the microneme proteins. It is a 218 kDa microneme protein from Eimeria ten Ella. In this study, RNA was extracted...
In this study, the expression of 14–3–3gamma and CLIC4 proteins in hippocampus and cortex surrounding the ischemia area was studied. The middle cerebral artery occlusion(MCAO) method was used to induce the focal cerebral ischemia in hippocampus and cortex and was identified with a pathological morphological method. 2, 3, 5-triphenyl tetrazolium chloride (TTC) staining showed the area of cerebral ischemia...
The purpose of this paper was to know the elderly diet and nutritional status of elderly apartments in Shandong province, then give some suggestions for improvement. The method of investigation was a continuous 3-day bookkeeping meanwhile conbing the retrospection, which lasts 2 months in 45 apartments of six regions (effective 38), Shandong province. The results is as follows: the composition of...
A full length dicer-like gene was cloned from 9311 (Oryza sativa indica) by RACE (GenBank accession No: DQ208406). It should be an OsDCL3b through homogeneous alignment and locate on chromosome 10. This gene might have alternative splicing transcripts. Real-time PCR results indicated that it expressed at different levels in root, stem, leaf and flower, respectively. The highest expression level of...
[Objective] The aim was to study the expression of cold resistant gene CAS19 of Gongnong No.2 Medicago sativa L. in tobacco. [Method] A pair of primers was designed according to nucleotide sequences of cold resistant gene CAS19 of M. sativa, and then RT-PCR was used to amplify the protein gene of CAS19, which was then cloned into pMD18-T vector and subcloned into expression vector PBI121. The recombination...
The objectives of this study were to evaluate the effects of different maturity on A.sparsifolia silage quality. Bud appearing (LF) , first flower appearing(LC), full blooming(LS), and first fruit appearing(LJ) A. sparsifolia were used in this experiment. Fore forages were harvested, chopped to ensiling in wide-mouth glass bottle, 150 days after ensiling, silages were sensorially evaluated and sampled...
Adolescent idiopathic scoliosis (AIS) is present in 2 to 4 percent of children between 10 and 16 years of age, which seriously affects the mental and physical health of young people while is defined as a lateral curvature of the spine greater than 10 degrees accompanied by vertebral rotation. The main risk factors for curve progression are a large curve magnitude, skeletal immaturity and female gender...
The model chicks was produced by continuous peritoneal injection of different concentration aluminium trichloride to investigate the effect of aluminum (Al) on calcium homeostasis in chicken brain at doses of Al3+ 0, 18.31, 27.47 and 36.62mg/kg BW/d lasting 60 days. The content of Al in brain tissues was measured by atomic absorption spectroscopy. The concentration of [Ca2+]i in fowl nerve cells was...
Complex network theory is utilized to explore the implication of protein domain content on evolution of eukaryotes. Comparative analysis of domains and their combination networks of eukaryotic organisms ranging over different phylogenetic groups demonstrate that: (1) topological features of domain combination network are correlated with organismal complexity; (2) globally central domains, defined...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.