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Radiofrequency ablation has been used to treat some types of cardiac arrhythmias. We have previously proposed an ARMAX model (non structural) to estimate the temperature in the tissue during ablation. Computer modeling has allowed us to study the temperature distribution by means of solving numerically theoretical models based on partial differential equations, which represent physical phenomena....
When developing microelectronic devices for biological applications it is often useful to simulate heterogeneous environments, e.g. metal electrodes in contact with aqueous electrolytes or living cells electrically stimulated. Both in the former and in the latter arises the influence of thin layers like electrodes polarization sheets and cell membranes. The numeric simulation of these systems using...
The foreign body reaction that the neural tissue develops around an implanted electrode contributes to insulate the probe and enhances the electrical and mechanical mismatch. It is a complex interaction among cells and soluble mediators and the knowledge of this phenomenon can benefits of formal and analytical methods that characterize the mathematical models. This work offers a lumped component model,...
The proposed method is intended to adjust the electrode potentials used in deep brain stimulation (DBS) with the consideration of both tissue transform and thermal effects caused by stimulation. During a typical DBS process, it is essential, for an effective treatment, to control the stimulation strength and region with varied applied electrode potentials. Some previous studies have been devoted for...
Mathematical model of homogeneous cardiac tissue is used to show that externally applied current can create changes of transmembrane potential in long distances from stimulating electrodes.
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