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The development of new technologies to monitor drugs concentration directly in patient's blood is absolutely required to succeed in personalized drug therapies. In this study, Etoposide - a well-known anti-cancer drug - has been chosen as model for cyclic voltammetry detection of drugs. Carbon nanotubes are chosen as electron-transfer mediators to enhance the system sensitivity. A very low frequency...
Monitoring of metabolic compounds in cell cultures can provide real-time information of cell line status. This is particularly important in those lines not fully known, as the case of embryonic and mesenchymal cells. On the other hand, such approach can pave the way to fully automated systems for growing cell cultures, when integrated in Petri dishes. To date, the main efforts emphasize the monitoring...
Monitoring of metabolic compounds, such as glucose and lactate, is extensively reported in literature, especially for clinical purposes. Instead, the application of such technologies for monitoring metabolites in cell cultures has not been explored. From one side, such devices can provide information to the current state-of-the-art of cell lines, particularly those which are not fully known, as stem...
This paper reports on the analytical performance of a disposable electrochemical sensor for the detection of hydrogen peroxide, using screen-printed carbon based electrodes (SPCEs) modified with a dispersion of multi-wall carbon nanotubes in chitosan (CHIT/MWCNT). The modified sensors showed an excellent electrocatalytic activity towards hydrogen peroxide, respect to the high overvoltage characterizing...
Multi-walled carbon nanotubes (MWNTs) were successfully manipulated by dielectrophoresis (DEP) to form electrical connection between interdigitated gold electrodes (IDEs) and were demonstrated to serve as gas sensor for NH3 detection. The MWNTs were suspended in ethanol and deposited on the IDEs under the effect of DEP. After the evaporation of ethanol, the MWNTs remained between the gaps of the IDEs...
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