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The chaos synchronization problem is investigated in a coronary artery system with periodic disturbance. Based on the Lyapunov stability theory and the comparison theorem, an effective impulsive law with variable control gains and impulsive intervals is designed to achieve synchronization of the chaotic coronary artery system. The upper bound of impulsive interval is given to ensure the stable synchronization...
There is huge amount of biomedical and biological literature online or in digital libraries. Moreover, new research papers are published with an exponential growth in recent years. So it is pressing and challenging to mine meaningful topics from massive biomedical literature. The mined topics are helpful to researchers for literature exploration and topic discovery. However, latent topics inferred...
Atherosclerosis is the most prevalent cardiovascular disease which affects millions of people globally each year. The development of atheroma is directly connected to the interaction of blood flow with the arterial wall. Therefore, the modeling of this interaction is of critical importance for the study of arterial blood flow mechanics and the progression of atherosclerosis. In this study, we use...
In this work, we propose a model of the coronary circulation based on hydraulic/electric analogy. This model aims to provide quantitative estimations of the distribution of flows and pressures across the coronary network for patients with stenoses of the left main coronary artery, left anterior descending artery and left circumflex branch, and chronic occlusion of the right coronary artery, undergoing...
Determining the stiffness (or compliance) of biological vascular vessels is of importance when investigating pathological conditions, the design of stents, vascular grafts, distal anastomotic connectors in coronary artery bypass surgery, and understanding of biological pressure sensors. This communication is concerned with determining appropriate values of the material constants associated with a...
In normal life the human body is quite often subjected to g-force. Prolonged exposure to such accelerations can generate significant effects on the blood circulation and its theological behavior depending on the configuration and geometry of the blood vessels. To analyze the effect of body acceleration in blood flow in arteries, blood is considered as a non-Newtonian fluid. The Navier-Stokes equations...
One of the central themes in addressing vascular disease is connected with the behavior of the arterial wall; its response to stimuli, its remodeling, the growth or stabilization of lesions and the interaction with implants and drugs. For the case of cerebral aneurysms, we are presenting an effort to embed computational simulation models capable of handling such processes within an IT framework that...
Blood flow in the large systemic artery is modeled using one-dimensional equations. Pulsatile 1-D Navier-Stokes solver incorporating fluid-wall interactions for a Newtonian fluid which predicts pressure and flow in the human artery is used for the numerical simulations. Blood flow and pressure in the artery is computed as functions of time and axial distance of the vessel. The blood flow is computed...
Diseased vessels experience a significantly different biomechanical environment than healthy vessels due to the presence of transitional and turbulent flow, which may be responsible for cell damage or plaque disruption. With an objective of investigating turbulent characteristics in a diseased vessel, direct numerical simulations were conducted based on a patient-specific carotid bifurcation with...
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