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article

Single‐shot spiral diffusion‐weighted imaging at 7T using expanded encoding with compressed sensing

Gabriel Varela‐Mattatall, Paul I. Dubovan, Tales Santini, Kyle M. Gilbert, more

Magnetic Resonance in Medicine > 90 > 2 > 615 - 623

Purpose The expanded encoding model incorporates spatially‐ and time‐varying field perturbations for correction during reconstruction. To date, these reconstructions have used the conjugate gradient method with early stopping used as implicit regularization. However, this approach is likely suboptimal for low‐SNR cases like diffusion or high‐resolution MRI. Here, we investigate the extent that

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...

article

Concomitant magnetic‐field compensation for 2D spiral‐ring turbo spin‐echo imaging at 0.55T and 1.5T

Zhixing Wang, Rajiv Ramasawmy, Xue Feng, Adrienne E. Campbell‐Washburn, more

Magnetic Resonance in Medicine > 90 > 2 > 552 - 568

Purpose To develop 2D turbo spin‐echo (TSE) imaging using annular spiral rings (abbreviated “SPRING‐RIO TSE”) with compensation of concomitant gradient fields and B₀ inhomogeneity at both 0.55T and 1.5T for fast T₂‐weighted imaging. Methods Strategies of gradient waveform modifications were implemented in SPRING‐RIO TSE for compensation of self‐squared concomitant gradient terms at the TE and across...

article

Latent signal models: Learning compact representations of signal evolution for improved time‐resolved, multi‐contrast MRI

Yamin Arefeen, Junshen Xu, Molin Zhang, Zijing Dong, more

Magnetic Resonance in Medicine > 90 > 2 > 483 - 501

Purpose To improve time‐resolved reconstructions by training auto‐encoders to learn compact representations of Bloch‐simulated signal evolution and inserting the decoder into the forward model. Methods Building on model‐based nonlinear and linear subspace techniques, we train auto‐encoders on dictionaries of simulated signal evolution to learn compact, nonlinear, latent representations. The proposed...

article

Quantitative MRI by nonlinear inversion of the Bloch equations

Nick Scholand, Xiaoqing Wang, Volkert Roeloffs, Sebastian Rosenzweig, more

Magnetic Resonance in Medicine > 90 > 2 > 520 - 538

Purpose Development of a generic model‐based reconstruction framework for multiparametric quantitative MRI that can be used with data from different pulse sequences. Methods Generic nonlinear model‐based reconstruction for quantitative MRI estimates parametric maps directly from the acquired k‐space by numerical optimization. This requires numerically accurate and efficient methods to solve the...

article

Parallel imaging reconstruction using spatial nulling maps

Jiahao Hu, Zheyuan Yi, Yujiao Zhao, Junhao Zhang, more

Magnetic Resonance in Medicine > 90 > 2 > 502 - 519

Purpose To develop a robust parallel imaging reconstruction method using spatial nulling maps (SNMs). Methods Parallel reconstruction using null operations (PRUNO) is a k‐space reconstruction method where a k‐space nulling system is derived using null‐subspace bases of the calibration matrix. ESPIRiT reconstruction extends the PRUNO subspace concept by exploiting the linear relationship between...

article

Behavioral and functional assessment of mice inner ear after chronic exposure to an ultrahigh B₀ field of 11.7 T or 17.2 T

Caroline Le Ster, Erwan Selingue, Rosline Poirier, Jean‐Marc Edeline, more

Magnetic Resonance in Medicine > 90 > 2 > 699 - 707

Purpose Assess short‐term and long‐term effects of chronic exposure to an ultrahigh static magnetic (B₀) field on mice inner ear in the context of MR safety of human scanning at 11.7 T. Methods Mice were chronically exposed to a B₀ field of 11.7 T or 17.2 T during ten 2‐h exposure sessions evenly distributed over a period of 5 weeks, resulting in a total of 20 h of exposure per mouse. During exposure...

article

Numerical fitting of Extrapolated semisolid Magnetization transfer Reference (NEMR) signals: Improved detection of ischemic stroke

Xingwang Yong, Shanshan Lu, Yi‐Cheng Hsu, Caixia Fu, more

Magnetic Resonance in Medicine > 90 > 2 > 722 - 736

Purpose To propose a novel Numerical fitting method of the Extrapolated semisolid Magnetization transfer Reference (NEMR) signal for quantifying the CEST effect. Theory and Methods Modified two‐pool Bloch‐McConnell equations were used to numerically fit the magnetization transfer (MT) and direct water saturation (DS) signals at far off‐resonance frequencies, which was subsequently extrapolated into...

article

The exchange rate of creatine CEST in mouse brain

Ziqin Zhang, Kexin Wang, Sooyeon Park, Anna Li, more

Magnetic Resonance in Medicine > 90 > 2 > 373 - 384

Purpose To estimate the exchange rate of creatine (Cr) CEST and to evaluate the pH sensitivity of guanidinium (Guan) CEST in the mouse brain. Methods Polynomial and Lorentzian line‐shape fitting (PLOF) were implemented to extract the amine, amide, and Guan CEST signals from the brain Z‐spectrum at 11.7T. Wild‐type (WT) and knockout mice with the guanidinoacetate N‐methyltransferase deficiency (GAMT...

article

Open‐source myocardial T₁ mapping with simultaneous multi‐slice acceleration: Combining an auto‐calibrated blipped‐bSSFP readout with VERSE‐MB pulses

Andreia S. Gaspar, Nuno A. Silva, Anthony N. Price, António M. Ferreira, more

Magnetic Resonance in Medicine > 90 > 2 > 539 - 551

Purpose Enabling fast and accessible myocardial T₁ mapping is crucial for extending its clinical application. We introduce Open‐MOLLI‐SMS combining simultaneous multi‐slice (SMS) with auto‐calibration and variable‐rate selective excitation (VERSE)‐multiband pulses to obtain all slices in a fast single‐shot T₁ mapping sequence. Methods Open‐MOLLI‐SMS was developed by integrating SMS with the open‐source...

article

Dynamic mode decomposition of dynamic MRI for assessment of pulmonary ventilation and perfusion

Efe Ilicak, Safa Ozdemir, Jascha Zapp, Lothar R. Schad, more

Magnetic Resonance in Medicine > 90 > 2 > 761 - 769

Purpose To introduce dynamic mode decomposition (DMD) as a robust alternative for the assessment of pulmonary functional information from dynamic non‐contrast‐enhanced acquisitions. Methods Pulmonary fractional ventilation and normalized perfusion maps were obtained using DMD from simulated phantoms as well as in vivo dynamic acquisitions of healthy volunteers at 1.5T. The performance of DMD was...

article

Highly accelerated intracranial time‐of‐flight magnetic resonance angiography using wave‐encoding

Yang Ji, Wenchuan Wu, Matthijs H. S. Buck, Thomas Okell, more

Magnetic Resonance in Medicine > 90 > 2 > 432 - 443

Purpose To develop an accelerated 3D intracranial time‐of‐flight (TOF) magnetic resonance angiography (MRA) sequence with wave‐encoding (referred to as 3D wave‐TOF) and to evaluate two variants: wave–controlled aliasing in parallel imaging (CAIPI) and compressed‐sensing wave (CS‐wave). Methods A wave‐TOF sequence was implemented on a 3 T clinical scanner. Wave‐encoded and Cartesian k‐space datasets...

article

Assessment of focal renal ischemia–reperfusion injury in a porcine model using hyperpolarized [1‐¹³C]pyruvate MRI

Uffe Kjærgaard, Nikolaj Bøgh, Esben Søvsø Szocska Hansen, Rasmus Stilling Tougaard, more

Magnetic Resonance in Medicine > 90 > 2 > 655 - 663

Purpose Ischemic injury in the kidney is a common pathophysiological event associated with both acute kidney injury and chronic kidney disease; however, regional ischemia–reperfusion as seen in thromboembolic renal disease is often undetectable and thus subclinical. Here, we assessed the metabolic alterations following subclinical focal ischemia–reperfusion injury with hyperpolarized [1‐¹³C]pyruvate...

article

RF‐induced heating for active implantable medical devices in dual parallel leads configurations at 1.5 T MRI

Wei Hu, Ran Guo, Qingyan Wang, Jianfeng Zheng, more

Magnetic Resonance in Medicine > 90 > 2 > 686 - 698

Purpose The Radiofrequency (RF)‐induced heating for an active implantable medical device (AIMD) with dual parallel leads is evaluated in this paper. The coupling effects between dual parallel leads are studied via simulations and experiments methods. The global transfer function technique is used to assess the RF‐induced heating for dual‐lead AIMDs inside four human body models. Methods RF‐induced...

article

A fast and practical computation method for magnetic resonance simulators

Hidenori Takeshima

Magnetic Resonance in Medicine > 90 > 2 > 752 - 760

Purpose This work aims to develop a fast and practical computation method for MR simulations. The computational cost of MR simulations is often high because magnetizations of many isochromats are updated using a small step size on the order of microseconds. There are two types of subsequences to be processed for the simulations: subsequences with and without RF pulses. While straightforward implementations...

article

Fat mitigation strategies to improve image quality of radial 4D flow MRI in obese subjects

A. M. K. Muntasir Shamim, Nikolaos Panagiotopoulos, Alma Spahic, David T. Harris, more

Magnetic Resonance in Medicine > 90 > 2 > 444 - 457

Purpose This study addresses the challenges in obtaining abdominal 4D flow MRI of obese patients. We aimed to evaluate spectral saturation and inner volume excitation as methods to mitigating artifacts originating from adipose signals, with the goal of enhancing image quality and improving quantification. Methods Radial 4D flow MRI acquisitions with fat mitigation (inner volume excitation [IVE]...

article

B₁ and magnetization decay correction for hyperpolarized ¹²⁹Xe lung imaging using sequential 2D spiral acquisitions

Abdullah S. Bdaiwi, Mariah L. Costa, Joseph W. Plummer, Matthew M. Willmering, more

Magnetic Resonance in Medicine > 90 > 2 > 473 - 482

Purpose To mitigate signal variations caused by inhomogeneous RF and magnetization decay in hyperpolarized ¹²⁹Xe ventilation images using flip‐angle maps generated from sequential 2D spiral ventilation images acquired in a breath‐hold. Images and correction maps were compared with those obtained using conventional, 2D gradient‐recalled echo. Theory and Methods Analytical expressions to predict signal...

article

Electromagnetic and RF pulse design simulation based optimization of an eight‐channel loop array for 11.7T brain imaging

Son Chu, Vincent Gras, Franck Mauconduit, Aurélien Massire, more

Magnetic Resonance in Medicine > 90 > 2 > 770 - 783

Purpose Optimization of transmit array performance is crucial in ultra‐high‐field MRI scanners such as 11.7T because of the increased RF losses and RF nonuniformity. This work presents a new workflow to investigate and minimize RF coil losses, and to choose the optimum coil configuration for imaging. Methods An 8‐channel transceiver loop‐array was simulated to analyze its loss mechanism at 499.415...

article

Unsupervised cycle‐consistent network using restricted subspace field map for removing susceptibility artifacts in EPI

Qingjia Bao, Weida Xie, Martins Otikovs, Liyang Xia, more

Magnetic Resonance in Medicine > 90 > 2 > 458 - 472

Purpose To design an unsupervised deep neural model for correcting susceptibility artifacts in single‐shot Echo Planar Imaging (EPI) and evaluate the model for preclinical and clinical applications. Methods This work proposes an unsupervised cycle‐consistent model based on the restricted subspace field map to take advantage of both the deep learning (DL) and the reverse polarity‐gradient (RPG) method...

article

Stochastic optimization of three‐dimensional non‐Cartesian sampling trajectory

Guanhua Wang, Jon‐Fredrik Nielsen, Jeffrey A. Fessler, Douglas C. Noll

Magnetic Resonance in Medicine > 90 > 2 > 417 - 431

Purpose Optimizing three‐dimensional (3D) k‐space sampling trajectories is important for efficient MRI yet presents a challenging computational problem. This work proposes a generalized framework for optimizing 3D non‐Cartesian sampling patterns via data‐driven optimization. Methods We built a differentiable simulation model to enable gradient‐based methods for sampling trajectory optimization....

article

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Single‐shot spiral diffusion‐weighted imaging at 7T using expanded encoding with compressed sensing

Concomitant magnetic‐field compensation for 2D spiral‐ring turbo spin‐echo imaging at 0.55T and 1.5T

Latent signal models: Learning compact representations of signal evolution for improved time‐resolved, multi‐contrast MRI

Quantitative MRI by nonlinear inversion of the Bloch equations

Parallel imaging reconstruction using spatial nulling maps

Behavioral and functional assessment of mice inner ear after chronic exposure to an ultrahigh B₀ field of 11.7 T or 17.2 T

Numerical fitting of Extrapolated semisolid Magnetization transfer Reference (NEMR) signals: Improved detection of ischemic stroke

The exchange rate of creatine CEST in mouse brain

Open‐source myocardial T₁ mapping with simultaneous multi‐slice acceleration: Combining an auto‐calibrated blipped‐bSSFP readout with VERSE‐MB pulses

Dynamic mode decomposition of dynamic MRI for assessment of pulmonary ventilation and perfusion

Highly accelerated intracranial time‐of‐flight magnetic resonance angiography using wave‐encoding

Assessment of focal renal ischemia–reperfusion injury in a porcine model using hyperpolarized [1‐¹³C]pyruvate MRI

RF‐induced heating for active implantable medical devices in dual parallel leads configurations at 1.5 T MRI

A fast and practical computation method for magnetic resonance simulators

Fat mitigation strategies to improve image quality of radial 4D flow MRI in obese subjects

B₁ and magnetization decay correction for hyperpolarized ¹²⁹Xe lung imaging using sequential 2D spiral acquisitions

Electromagnetic and RF pulse design simulation based optimization of an eight‐channel loop array for 11.7T brain imaging

Unsupervised cycle‐consistent network using restricted subspace field map for removing susceptibility artifacts in EPI

Stochastic optimization of three‐dimensional non‐Cartesian sampling trajectory

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