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Identifying the technology trends, key patents to be aware of, the key players active in the field, the product areas that are heavily patented or scarcely addressed, and the focus of a company's competitors represent crucial aspects of developing a successful strategic plan, determining a company's freedom to make and sell their product, and focusing future research & product development efforts...
We present two novel SERS substrates which allow easily achievable sub-10 nm gaps — ‘Nanoparticles inside Nanolines’ and ‘Nanofingers inside Nanowires’. Theoretical studies based on Finite Difference Time Domain (FDTD) modelling as well as large-are fabrication methodologies for developing these substrates are discussed.
In this paper, graphene for SERS molecular sensors is reviewed along with a report of new innovations. Arrays of silver nanoparticles were selectively deposited on copper, on which discrete graphene domains had been synthesized. Closely spaced silver nanoparticles create strong local electric fields by means of laser induced plasmonic coupling. Signal intensity measured from Raman scattering of low...
Understanding the behavior and fate of engineered nanomaterials (ENMs) released to the environment requires measurement of their physicochemical properties in relevant media. Specialized instrumentation is required to be able to detect their changes in physicochemical characteristics (such as agglomeration and dissolution) as ENMs move from the manufactured state to the exposure pathway and ultimately...
The objective of this study was to demonstrate a proof of concept for a technology platform which could produce engineered hydroxyapatite nanoparticles with respect to size, shape and morphology with ease and adapt it to a continuous production line. The conventional processes that are used in the production of hydroxyapatite are not only cumbersome but also expensive since the precursors are of high...
The transition of highly functional nanomaterials into scalable composite manufacturing processes often leads to the deterioration of the desired nanomaterial properties. In this work, selective coating methodologies are employed to protect optically-tailored nanoplasmonic materials against the high temperature/high shear environments associated with extrusion and injection molded polymer nanocomposites...
A synthesis of gold nanoparticles (GNPs) dispersion in an organic solvent by a glass microfluidic device was reported in this paper. Brust-Schiffrin synthesis method can prepare GNPs dispersion in toluene. However, since the method is a complex synthesis process such as mixing and separation, control of nanoparticle size was difficult. A glass microfluidic device with mixing and separation functions...
Food supply and food safety are the key global public health issues, and are particularly important in heavily populated countries. Rapid industrialization and modernization in the developing world are having profound effects on food supply and food safety. In the age of globalization, the makeup of the international food industry is constantly transforming. Global food retail sales stand at about...
To evaluate a multifunctional microcapsule for cartilage tissue engineering, we developed a brand new amphiphilic material grafting Hyaluronic acid (HA) on hexanoic anhydride modified gelatin. The material formed microcapsules (HA-AGMC) loaded with superparamagnetic iron oxide (SPIO) and TGF-β1 can stimulate chondrogenic differentiation by the combination of biochemical and biophysical stimulation.
In this study, NiFe2O4/RGO (reduced graphene oxide) were prepared successfully via a facile method based on solvothermal method. The as-synthesized NiFe2O4/RGO nanoparticles were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and N2 adsorption/desorption. To investigate the catalytic activity of the as-synthesized NiFe2O4/RGO nanoparticles,...
Gold nanoplates (NPs) were fabricated through a facile hydrothermal method with cetyltrimethylammonium chlorine (CTAC) as a surfactant agent. The morphology and size of the gold NPs could be manipulated by changing the molar ratio of ([CTAC]/[HAuCl4] during the preparation. Triangular, truncated triangular and hexagonal gold nanoplates can be obtained and the sizes of these gold NPs can be varied...
Paramagnetic nanoparticles actuated by external magnetic fields with effective and fast responses, can serve as microrobotic end-effectors with great potential for targeted delivery of drugs. In this paper, we report that using a rotating magnetic field, suspended paramagnetic particles are gathered into a vortex-like swarm. Moreover, by increasing the rotating frequency of the magnetic fields, multiple...
Neurodegenerative disorder diseases have been perplexing physicians and scientists for many years. There is considerable interest in developing diagnostic nanotools for diagnosis and therapeutic treatment strategies for the neuron diseases. However, a key challenge remains in selection of suitable surface to overcome the nano-bio interface issue as many nanoparticles indicate instability when administered...
Alzheimer's disease (AD), a type of progressive neurodegenerative disorder disease, has affected more than 5 million Americans and has already become a primary cause of death for older people in the United States, which is just behind heart disease and cancer. The production and aggregation of amyloid-beta (Aβ) peptide in plaques in extracellular spaces, as well as in the walls of blood vessels, have...
The case involving Low-density Polyethylene (LDPE) containing nano-MgO is revisited here with the main aim of verifying the effect of the fabrication technique. LDPE powder and MgO unfunctionalized nanoparticles were used in conjunction with an impact ball-milling method. Samples consisting of neat LDPE and nanocomposites containing 1 and 5 wt% of MgO were prepared. Several material and dielectric...
This paper presents a Monte Carlo computational approach for nanoscale simulation of photocatalytic activity of spherical titania nanoparticles in a cement substrate. The work represents the first theoretical attempt to address the kinetics of a photocatalytic process occurring at nano-TiO2 inserted in a cement matrix. The herein reported Monte Carlo simulation includes charge diffusion and trapping,...
We demonstrate electron transport characteristics of newly synthesized NiO nanoparticles on p-type Si substrate using scanning tunneling microscopy (STM). The resistivity and conductivity were determined to be 1.7×104 Ω.cm and 5.8×10−5 Ω.cm for Ni(OH)2 and 3.1×105 Ω.cm and 3.2×10−6 Ω.cm for NiO, respectively. Additionally, we also exemplify the characteristics features of graphene flakes with NiO...
Targeted drug delivery through the use of swimming microorganisms known as Magnetococcus marinus MC-1 magnetotactic bacteria (or MTB) [1] acting as nanorobots loaded with therapeutic agents has been demonstrated [2]. While the role of magnetic nanoparticles (MNPs) in medicine and more specifically drug delivery enhancement is generally known [3], this study aims to couple the previously mentioned...
Intravenous systemic injection of fluidMAG-PMO magnetic nanoparticles followed by hyperthermia of the brain has previously shown to be a promising method for overcoming the blood-brain barrier; the great challenge of drug delivery to the brain. This study explores the possibility of utilizing magnetotactic bacteria as micro-carriers for fluidMAG-ARA magnetic nanoparticles as means of direct targeting...
In this work, Scanning Microwave Microscopy (SMM) is applied to breast cancer cells MCF-7 treated by fullerene (C60), in order to provide simultaneous topographic and electromagnetic characterization of sample surface. The exceptional properties of fullerene, like its lipophilicity and its ability to be functionalized with proteins and nucleic acids, make its use very promising for drug delivery and...
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