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The impact of preformed and de novo HLA‐DP antibodies after renal transplantation remains controversial and unclear. To address the clinical relevance of HLA‐DP antibodies on the outcomes in renal transplantation, we performed a random effect model meta‐analysis through a systematic review from inception to December 31, 2021. The outcome was graft loss or acute rejection. Finally five articles were...
Several HLA allelic variants have been associated with protection from or susceptibility to infectious and autoimmune diseases. Here, we examined whether specific HLA alleles would be associated with different Mycobacterium tuberculosis (Mtb) infection outcomes. The HLA alleles present at the ‐A, ‐B, ‐C, ‐DPA1, ‐DPB1, ‐DQA1, ‐DQB1, ‐DRB1, and ‐DRB3/4/5 loci were determined in a cohort of 636 individuals...
Eplet 44KM is currently listed in the HLA Epitope Registry but does not adhere to the eplet definition of an amino acid configuration within a 3.5 Å radius. Eplet 44KM has been previously redefined to the antibody‐verified reactivity pattern 44K/150V/158V, based on reactivity analysis of monoclonal antibody VDK1D12. Since the three residues are always simultaneously present on common HLA alleles,...
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